1727

January–June

• February 11 - Spain besieges Gibraltar, in order to recapture the territory.
• February 2 - Johann Sebastian Bach's solo cantata, Ich habe genug, BWV 82, premieres in Leipzig.
• February 20 - German composer George Frideric Handel becomes a British subject.
• April 11 - Johann Sebastian Bach's St Matthew Passion premieres at St. Thomas Church, Leipzig.
• May 12 - History of the Moravian Church: The 18th century renewal: The Brotherly Agreement is adopted by the Moravian Church community at Herrnhut, under the influence of Count Nicolaus Zinzendorf, beginning the Church's renewal.
• May 31 - The Royal Bank of Scotland is founded by Royal Charter in Edinburgh.
• June 11 - George, Prince of Wales, becomes King George II of Great Britain, on the death of his father.
• June 27 - Uxbridge, Massachusetts, is incorporated as a town.

  July–December

• July - History of the Ursulines in New Orleans: Seventeen Ursuline Sisters from France land in New Orleans, Louisiana, where they found the orphanage which is the predecessor of Catholic Charities and the Ursuline Academy, making the latter the oldest continuously-operating school for girls, and the oldest Catholic school in the United States.
• August 13 - History of the Moravian Church: The 18th century renewal: The Moravian Church community at Herrnhut undergoes a Pentecostalist experience.
• August 30 - Anne, eldest daughter of King George II of Great Britain, is given the title Princess Royal.
• September 8 - A barn fire during a puppet show in the village of Burwell, Cambridgeshire, England, kills 78 people, many of them children. Another report says that all but six of the 160 persons assembled were killed in the accidental fire.
• October 11 - George II of Great Britain is crowned. Handel's Coronation Anthems are composed for the event, including Zadok the Priest, which has been played at every subsequent Coronation of the British monarch.
• November 18 - An earthquake in Tazriz, Persia kills 77,000.
• November 21 - The Netherlands signs the Treaty of Seville.
• November 27 - The foundation stone of the Jerusalem's Church in Berlin is laid.

  Date unknown

• An old woman known as Janet Horne of Loth, Sutherland becomes the last alleged witch in the British Isles to be executed, when she is burned at the stake in Dornoch, Scotland.
• The first Amish move to North America.
• 1727-1800 - Lt. Col. Francisco de Mello Palheta smuggles coffee seeds to Brazil in a bouquet, starting a coffee empire.