In and, he appeared in 39 games for the Royals, hitting.163 with one home run and eleven RBI. He was acquired by the Oakland Athletics in exchange for cash considerations on November 28, 2006.
Murphy was signed by the Baltimore Orioles to a minor league deal with a spring training invitation for the 2009 season.
Florida/Miami Marlins
On December 14, 2009, Murphy signed a minor league contract with the Florida Marlins with an invitation to spring training. He was called up on July 3, 2010. He hit a walk-off home run to defeat the Colorado Rockies on July 19, 2010. It was the first walk-off home run by the Marlins that season. Continuing to play with the Marlins in a utility role, Murphy's season was cut short on September 1 when he dislocated his right wrist on a tough catch in the fourth inning. He had surgery the following day, ending one of his most successful seasons. Murphy became a free agent on October 15 after refusing a minor league assignment. He was re-signed to a minor league contract on October 18. , triple-A affiliates of the Miami Marlins, in In 2012, Murphy ended up on the 25-man roster for the Marlins going into opening day. On June 10, 2012, the Marlins designated Murphy for assignment to make room for Gaby Sánchez. He passed waivers and was sent to the New Orleans Zephyrs. On July 27, he was recalled by the Marlins after a trade sent Hanley Ramírez and Randy Choate to the Los Angeles Dodgers for Nathan Eovaldi and Scott McGough. On August 3, he pulled his left hamstring against the Washington Nationals. Five days later, he was placed on the 15-day DL. On August 19, he and Emilio Bonifacio were both reinstated. Murphy ended the year with three homers, six doubles, two triples, 12 RBIs, nine walks and one stolen base while batting.216 in 116 at-bats. On October 18, 2012, Murphy was outrighted off the Marlins' 40-man roster and elected free agency.
In April 2013, Murphy signed with the Chicago Cubs. Murphy hit a career-high 11 home runs in 2013 with Chicago, leading to him signing a one-year deal worth $825,000 with the Cubs after the season. Murphy also underwent surgery for a torn meniscus he had originally injured in 2009.
On March 26, 2014, Murphy was claimed off waivers from the Chicago Cubs by the Texas Rangers. He was designated for assignment on July 7. With the Rangers, he hit.196, with 4 homers, 14 RBIs, and 11 walks. He was released on July 9.
Murphy signed with Atlanta Braves on August 16, 2014.
Second stint with the Brewers
Murphy re-signed with the Milwaukee Brewers for the 2015 season and was assigned to AAA Colorado Springs Sky Sox. On August 2, 2015, Murphy was released by the Brewers.
Coaching
On February 23, 2016, the Toronto Blue Jays hired Murphy to be their new hitting coach for the Class-ALansing Lugnuts for the 2016 season. Murphy became the hitting coach for the Advanced-A Dunedin Blue Jays on January 10, 2018. After spending the 2019 season as the hitting coach for the Double-ANew Hampshire Fisher Cats, Murphy was named the manager for Dunedin on January 31, 2020.
