The station first signed on the air on August 1, 1994 as WFCT; the station was founded by Paxson Communications, which was renamed Ion Media Networks in 2007. It originally ran an all-infomercial format as an affiliate of the Paxson-owned Infomail TV Network, and also carried programming from The Worship Network during the overnight hours. The station also broadcast games from the now-defunct Atlanta Knightsminor league hockey franchise, which was affiliated with the NHL's Tampa Bay Lightning. At the time, Paxson also owned a chain of radio stations in Florida. Paxson's Tampa Bay radio cluster regularly received commercial time on WFCT; this ended when Paxson sold off his radio and billboard businesses to fund start up operations for the Pax TV network. The station changed its call letters to WXPX-TV in 1998; the station then became a charter owned-and-operated station of Pax TV when it debuted on August 31 of that year, after which it rebranded as "Pax 66". The Worship Network and infomercial remained on the station's schedule but it also carried the network's family-oriented programming. From 2004 to 2008, WXPX became the over-the-air broadcaster of the Tampa Bay Devil RaysMajor League Baseball franchise, airing a number of games that were not televised on a national broadcast or cable network. It also carried NBA games from the Orlando Magic through the syndicated Magic Television Network. The rights to those games later exclusively moved to regional sports networksFox Sports Florida and Sun Sports.
In 2000, WXPX entered into a news share agreement with NBC affiliate WFLA-TV as a result of NBC's management agreement with Pax TV. Unlike other Pax stations that rebroadcast newscasts seen on the originating station on a half-hour delay at minimum, the WFLA newscasts aired on WXPX were initially broadcast live and produced specifically for the station; the newscasts, titled News Channel 8 on PAX, aired weeknights at 7 and 10 p.m.. Due to poor ratings of the live newscasts, in 2002, the newscasts switched to pre-recorded broadcasts of WFLA's 6 and 11 p.m. newscasts airing at 7 and 11:30 p.m.. The WFLA agreement ended on June 30, 2005, when Paxson dissolved news share agreements on all of its stations. The only local non-brokered programming currently seen on WXPX is a local public affairs programi on Tampa; the station also previously aired Miccosukee Magazine.