Trichodiene synthase


In enzymology, a trichodiene synthase is an enzyme that catalyzes the chemical reaction
Hence, this enzyme has one substrate, trans,trans-farnesyl diphosphate, and two products, trichodiene and diphosphate.
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is trans,trans-farnesyl-diphosphate diphosphate-lyase . Other names in common use include trichodiene synthetase, sesquiterpene cyclase, and trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase. This enzyme participates in terpenoid biosynthesis.

Structural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes,,,,,,,, and.