List of enzymes
This page lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission numbering system. For a list of the EC numbers themselves, see:
- List of EC numbers
- List of EC numbers
- List of EC numbers
- List of EC numbers
- List of EC numbers
- List of EC numbers
[:Category:Oxidoreductases] (EC 1) ([Oxidoreductase])
- Dehydrogenase
- Luciferase
- DMSO reductase
[:Category:EC 1.1] (act on the CH-OH group of donors)
- :Category:EC 1.1.1
- *Alcohol dehydrogenase
- *Alcohol dehydrogenase
- *Homoserine dehydrogenase
- *Aminopropanol oxidoreductase
- *Diacetyl reductase
- *Glycerol dehydrogenase
- *Propanediol-phosphate dehydrogenase
- *glycerol-3-phosphate dehydrogenase
- *D-xylulose reductase
- *L-xylulose reductase
- *Lactate dehydrogenase
- *Malate dehydrogenase
- *Isocitrate dehydrogenase
- *HMG-CoA reductase
- :Category:EC 1.1.2
- :Category:EC 1.1.3
- *Glucose oxidase
- *L-gulonolactone oxidase
- *Thiamine oxidase
- *Xanthine oxidase
- :Category:EC 1.1.4
- :Category:EC 1.1.5
- :Category:EC 1.1.99
[:Category:EC 1.2] (act on the aldehyde or oxo group of donors)
- :Category:EC 1.2.1
- *Acetaldehyde dehydrogenase
- *Glyceraldehyde 3-phosphate dehydrogenase
- *Pyruvate dehydrogenase
- :Category:EC 1.2.4
- *Oxoglutarate dehydrogenase
[:Category:EC 1.3] (act on the CH-CH group of donors)
- :Category:EC 1.3.1
- *Biliverdin reductase
- :Category:EC 1.3.2
- :Category:EC 1.3.3
- *Protoporphyrinogen oxidase
- :Category:EC 1.3.5
- :Category:EC 1.3.7
- :Category:EC 1.3.99
[:Category:EC 1.4] (act on the CH-NH2 group of donors)
- :Category:EC 1.4.3
- *Monoamine oxidase
[:Category:EC 1.5] (act on CH-NH group of donors)
- :Category:EC 1.5.1
- *Dihydrofolate reductase
- *Methylenetetrahydrofolate reductase
- :Category:EC 1.5.3
- *Sarcosine oxidase
- *Dihydrobenzophenanthridine oxidase
- :Category:EC 1.5.4
- :Category:EC 1.5.5
- :Category:EC 1.5.7
- :Category:EC 1.5.8
- :Category:EC 1.5.99
[:Category:EC 1.6] (act on NADH or NADPH)
- :Category:EC 1.6.1
- :Category:EC 1.6.2
- :Category:EC 1.6.3
- Category:EC 1.6.4 now :Category:EC 1.8.1
- :Category:EC 1.6.5
- *NADH dehydrogenase
- :Category:EC 1.6.6
- Category:EC 1.6.7 now :Category:EC 1.18.1
- Category:EC 1.6.8 now :Category:EC 1.5.1
- :Category:EC 1.6.99
[:Category:EC 1.7] (act on other nitrogenous compounds as donors)
- :Category:EC 1.7.1
- :Category:EC 1.7.2
- :Category:EC 1.7.3
- *Urate oxidase
- :Category:EC 1.7.7
- :Category:EC 1.7.99
- *Nitrite reductase
- *Nitrate reductase
[:Category:EC 1.8] (act on a sulfur group of donors)
- :Category:EC 1.8.1
- *Glutathione reductase
- *Thioredoxin reductase
- :Category:EC 1.8.2
- :Category:EC 1.8.3
- *Sulfite oxidase
- :Category:EC 1.8.4
- :Category:EC 1.8.5
- Category:EC 1.8.6 deleted, included in EC 2.5.1.18
- :Category:EC 1.8.7
- :Category:EC 1.8.98
- :Category:EC 1.8.99
[:Category:EC 1.9] (act on a [heme] group of donors)
- :Category:EC 1.9.3
- *Cytochrome c oxidase
- :Category:EC 1.9.6
- Category:EC 1.9.99 transferred, now EC 1.9.98.1
[:Category:EC 1.10] (act on diphenol">benzenediol">diphenols and related substances as donors)
- :Category:EC 1.10.1
- :Category:EC 1.10.2
- *Coenzyme Q - cytochrome c reductase
- :Category:EC 1.10.3
- *Catechol oxidase
- *Laccase
- :Category:EC 1.10.99
[:Category:EC 1.11] (act on [peroxide] as an acceptor -- [peroxidase]s)
- :Category:EC 1.11.1
- *Cytochrome c peroxidase
- *Catalase
- *Myeloperoxidase
- *Thyroid peroxidase
- *Glutathione peroxidase
[:Category:EC 1.12] (act on hydrogen as a donor)
- :Category:EC 1.12.1
- :Category:EC 1.12.2
- :Category:EC 1.12.5
- :Category:EC 1.12.7
- :Category:EC 1.12.98
- :Category:EC 1.12.99
[:Category:EC 1.13] (act on single donors with incorporation of molecular oxygen)
- :Category:EC 1.13.11
- *4-hydroxyphenylpyruvate dioxygenase
- :Category:EC 1.13.12
- *Renilla-luciferin 2-monooxygenase
- *Cypridina-luciferin 2-monooxygenase
- *Firefly luciferase
- *Watasenia-luciferin 2-monooxygenase
- *Oplophorus-luciferin 2-monooxygenase
[:Category:EC 1.14] (act on paired donors with incorporation of molecular oxygen)
- Cytochrome P450 oxidase
- :Category:Cytochrome P450
- *Aromatase
- *CYP2D6
- *CYP2E1
- *CYP3A4
- *Cytochrome P450 oxidase
- :Category:EC 1.14.12
- *Nitric oxide dioxygenase
- :Category:EC 1.14.13
- *Nitric oxide synthase
- :Category:EC 1.14.14
- *Aromatase
- *CYP2D6
- *CYP2E1
- *CYP3A4
- :Category:EC 1.14.16
- *Phenylalanine hydroxylase
- :Category:EC 1.14.18
- *Tyrosinase
[:Category:EC 1.15] (act on superoxide radicals as acceptors)
- :Category:EC 1.15.1
- *Superoxide dismutase
[:Category:EC 1.16] (oxidize metal ions)
- :Category:EC 1.16.3
- *Ceruloplasmin
[:Category:EC 1.17] (act on CH or CH2 groups)
- :Category:EC 1.17.1
- *Leucoanthocyanidin reductase
- *Xanthine dehydrogenase
- *Nicotinate dehydrogenase
- *4-hydroxy-tetrahydrodipicolinate reductase
- :Category:EC 1.17.2
- *Nicotinate dehydrogenase
- :Category:EC 1.17.3
- *Xanthine oxidase
- :Category:EC 1.17.4
- *Ribonucleotide reductase
- *Ribonucleoside-triphosphate reductase
- *Vitamin K epoxide reductase
- *Vitamin-K-epoxide reductase
- *Vitamin-K-epoxide reductase
- *RRM1
- *RRM2
- *RRM2B
- :Category:EC 1.17.5
- *Caffeine dehydrogenase
- :Category:EC 1.17.7
- :Category:EC 1.17.99
[:Category:EC 1.18] (act on iron-sulfur proteins as donors)
- :Category:EC 1.18.6
- *Nitrogenase
[:Category:EC 1.19] (act on reduced flavodoxin as donor)
- :Category:EC 1.19.6
- *Nitrogenase
[:Category:EC 1.20] (act on phosphorus or arsenic as donors)
- :Category:EC 1.20.1
- :Category:EC 1.20.2
- :Category:EC 1.20.4
- *Arsenate reductase
- *Glutaredoxin
- :Category:EC 1.20.9
- :Category:EC 1.20.99
[:Category:EC 1.21] (act on X-H and Y-H to form an X-Y bond)
- :Category:EC 1.21.1
- *Iodotyrosine deiodinase
- :Category:EC 1.21.3
- *Isopenicillin N synthase
- *Tetrahydrocannabinolic acid synthase
- :Category:EC 1.21.4
- :Category:EC 1.21.99
- *Thyroxine 5-deiodinase
- *Iodothyronine deiodinase and
[:Category:EC 1.97] (other oxidoreductases)
- :Category:EC 1.97.1
- *Deiodinase
[:Category:Transferases] (EC 2) ([Transferase])
- Glutathione S-transferase
[:Category:EC 2.1] (transfer one-carbon groups, [Methylase])
- :Category:EC 2.1.1
- *Catechol-O-methyl transferase
- *DNA methyltransferase,,
- *Histone methyltransferase ,
- :Category:EC 2.1.3
- *Aspartate transcarbamoylase
- *Ornithine transcarbamoylase
[:Category:EC 2.2] (transfer [aldehyde] or [ketone] groups)
- :Category:EC 2.2.1
- *Transketolase
- *Transaldolase
- *Acetolactate synthase
- *2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
[:Category:EC 2.3] (acyltransferases)
- :Category:EC 2.3.1
- *Aminolevulinic acid synthase
- *Choline acetyltransferase
- :Category:EC 2.3.2
- *Factor XIII
- *Gamma glutamyl transpeptidase
- *Transglutaminase
[:Category:EC 2.4] (glycosyltransferases)
- :Category:EC 2.4.2
- *Hypoxanthine-guanine phosphoribosyltransferase
- :Category:EC 2.5.1
- *Thiaminase
[:Category:EC 2.5] (transfer [alkyl] or [aryl] groups, other than [methyl] groups)
- *Flavin prenyltransferase
[:Category:EC 2.6] (transfer nitrogenous groups)
- :Category:EC 2.6.1
- *Alanine transaminase
- *Aspartate transaminase
[:Category:EC 2.7] (transfer phosphorus-containing groups)
- :Category:EC 2.7.2
- *Butyrate kinase
[:Category:EC 2.8] (transfer sulfur-containing groups)
- : Thiosulfate sulfurtransferase
- : 3-mercaptopyruvate sulfurtransferase
- : Thiosulfate--thiol sulfurtransferase
- : tRNA uracil 4-sulfurtransferase
- : Thiosulfate--dithiol sulfurtransferase
- : Biotin synthase
- : Cysteine desulfurase
- : Lipoyl synthase
- : Molybdenum cofactor sulfurtransferase
- : Thiazole synthase
- : Molybdopterin synthase sulfurtransferase
- : Molybdopterin synthase
- : tRNA-uridine 2-sulfurtransferase
- : tRNA-5-taurinomethyluridine 2-sulfurtransferase
- : tRNA-5-methyluridine 2-sulfurtransferase
[:Category:EC 2.9] (transfer selenium-containing groups)
- : L-seryl-tRNA selenium transferase
- :
[:Category:Hydrolases] (EC 3) ([Hydrolase])
- Hydrolytic enzyme
[:Category:EC 3.1] (act on [ester] bonds)
- Nuclease
- Endonuclease
- Exonuclease
- :Category:EC 3.1.1
- *Acid hydrolase
- *Phospholipase A
- *Acetylcholinesterase
- *Cholinesterase
- *Lipoprotein lipase
- :Category:EC 3.1.2
- *Ubiquitin carboxy-terminal hydrolase L1
- :Category:EC 3.1.3
- *Phosphatase
- *Alkaline phosphatase
- *Fructose bisphosphatase
- :Category:EC 3.1.4
- *Phospholipase C
- *CGMP specific phosphodiesterase type 5
- *Phospholipase D
- :Category:EC 3.1.21
- *Restriction enzyme Type 1
- *Restriction enzyme Type 2
- *Restriction enzyme Type 3
- *Restriction enzyme Type 4
- *Deoxyribonuclease I
- :Category:EC 3.1.26
- *RNase H
- :Category:EC 3.1.27
- *Ribonuclease
[:Category:EC 3.2] (act on sugars - [glycosylases])
- :Category:EC 3.2.1
- *Amylase
- *Sucrase
- *Chitinase
- *Lysozyme
- *Maltase
- *Lactase
- *Beta-galactosidase
- *Hyaluronidase
[:Category:EC 3.3] (act on [ether] bonds)
- :Category:EC 3.3
- Adenosylmethionine hydrolase
- S-adenosyl-L-homocysteine hydrolase
- Alkenylglycerophosphocholine hydrolase
- Alkenylglycerophosphoethanolamine hydrolase
- Cholesterol-5,6-oxide hydrolase
- Hepoxilin-epoxide hydrolase
- Isochorismatase
- Leukotriene-A4 hydrolase
- Limonene-1,2-epoxide hydrolase
- Microsomal epoxide hydrolase
- Trans-epoxysuccinate hydrolase
[:Category:EC 3.4] (act on [peptide bond]s - [Peptidase])
- :Category:EC 3.4.11
- *Alanine aminopeptidase
- :Category:EC 3.4.15
- *Angiotensin converting enzyme
- :Category:EC 3.4.21
- *Serine protease
- *Chymotrypsin
- *Trypsin
- *Thrombin
- *Factor X
- *Plasmin
- *Acrosin
- *Factor VII
- *Factor IX
- *Prolyl oligopeptidase
- *Factor XI
- *Elastase
- *Factor XII
- *Proteinase K
- *Tissue plasminogen activator
- *Protein C
- :Category:EC 3.4.22
- *Separase
- :Category:EC 3.4.23
- *Pepsin
- *Rennet
- *Renin
- *Trypsinogen and
- *Plasmepsin
- :Category:EC 3.4.24
- *Matrix metalloproteinase
- :Category:EC 3.4.25
- *Metalloendopeptidase
[:Category:EC 3.5] (act on carbon-nitrogen bonds, other than peptide bonds)
- :Category:EC 3.5.1
- *Urease
- :Category:EC 3.5.2
- *Beta-lactamase
- :Category:EC 3.5.3
- *Arginase
- :Category:EC 3.5.4
- *Adenosine deaminase
- *GTP cyclohydrolase I
- :Category:EC 3.5.5
- *Nitrilase
[:Category:EC 3.6] (act on [acid anhydride]s)
- :Category:EC 3.6.1
- *Helicase
- *DnaB helicase
- *RecQ helicase
- :Category:EC 3.6.3
- *ATPase
- *NaKATPase
- *ATP synthase
[:Category:EC 3.7] (act on carbon-carbon bonds)
- Kynureninase
[:Category:EC 3.8] (act on [halide] bonds)
- EC 3.8.1.3 Haloacetate dehalogenase
[:Category:EC 3.9] (act on phosphorus-nitrogen bonds)
- : Phosphoamidase
- : Protein arginine phosphatase
- : Phosphohistidine phosphatase
[:Category:EC 3.10] (act on sulfur-nitrogen bonds)
- : N-sulfoglucosamine sulfohydrolase
- : Cyclamate sulfohydrolase
[:Category:EC 3.11] (act on carbon-phosphorus bonds)
- : Phosphonoacetaldehyde hydrolase
- : Phosphonoacetate hydrolase
- : Phosphonopyruvate hydrolase
[:Category:EC 3.12] (act on sulfur-sulfur bonds)
- : Trithionate hydrolase
[:Category:EC 3.13] (act on carbon-sulfur bonds)
- : UDP-sulfoquinovose synthase
- : 2'-hydroxybiphenyl-2-sulfinate desulfinase
- : 3-sulfinopropanoyl-CoA desulfinase
- : Carbon disulfide hydrolase
- : -S-L-cysteine hydrolase
- : Carbonyl sulfide hydrolase
- : S-adenosyl-L-methionine hydrolase
[:Category:Lyases] (EC 4) ([Lyase])
[:Category:EC 4.1] (carbon-carbon [lyase]s)
- :Category:EC 4.1.1
- *Ornithine decarboxylase
- *Uridine monophosphate synthetase
- *Aromatic-L-amino-acid decarboxylase
- *RubisCO
- :Category:EC 4.1.2
- *Fructose-bisphosphate aldolase
[:Category:EC 4.2] (carbon-oxygen [lyase]s)
- :Category:EC 4.2.1
- *Carbonic anhydrase
- *Tryptophan synthase
[:Category:EC 4.3] (carbon-nitrogen [lyase]s)
- :Category:EC 4.3.1
- *Phenylalanine ammonia-lyase
[:Category:EC 4.4] (carbon-sulfur [lyase]s)
- :Category:EC 4.4.1
- *Cystathionine gamma-lyase
- *Cystathionine beta-lyase
- *Leukotriene C4 synthase
[:Category:EC 4.5] (carbon-halide [lyase]s)
- :Category:EC 4.5.1
- *Dichloromethane dehalogenase
- *Halohydrin dehalogenase
[:Category:EC 4.6] (phosphorus-oxygen [lyase]s)
- :Category:EC 4.6.1
- *Adenylate cyclase
- *Guanylate cyclase
[:Category:Isomerases] (EC 5) ([Isomerase])
[:Category:EC 5.1] (racemases and epimerases)
- :Category:EC 5.1.1
- Amino-acid racemase: Phenylalanine racemase
- Serine racemase
- :Category:EC 5.1.2
- Mandelate racemase
- :Category:EC 5.1.3
- UDP-glucose 4-epimerase
- :Category:EC 5.1.99
- Methylmalonyl CoA epimerase
[:Category:EC 5.2] (cis-trans-isomerases)
- :Category:EC 5.2
- FKBP: FKBP1A
- FKBP1B
- FKBP2
- FKBP3
- FKBP5
- FKBP6
- FKBP8
- FKBP9
- FKBP10
- FKBP52
- FKBPL
- Cyclophilin
- Parvulin
- Prolyl isomerase
- 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
- Beta-carotene isomerase
- Farnesol 2-isomerase
- Furylfuramide isomerase
- Linoleate isomerase
- Maleate isomerase
- Maleylacetoacetate isomerase
- Maleylpyruvate isomerase
- Parvulin
- Photoisomerase
- Prolycopene isomerase
- Prolyl isomerase
- Retinal isomerase
- Retinol isomerase
- Zeta-carotene isomerase
[:Category:EC 5.3] (intramolecular">Intramolecular reaction">intramolecular [oxidoreductase]s)
- :Category:EC 5.3.3
- *Enoyl CoA isomerase
- :Category:EC 5.3.4
- *Protein disulfide isomerase
[:Category:EC 5.4] (intramolecular [transferase]s -- [mutase]s)
- :Category:EC 5.4.2
- *Phosphoglucomutase
[:Category:EC 5.5] (intramolecular [lyase]s)
[:Category:EC 5.99] (other isomerases)
- :Category:EC 5.99.1
- *Topoisomerase
[:Category:Ligases] (EC 6) ([Ligase])
[:Category:EC 6.1] (form carbon-oxygen bonds)
- :Category:EC 6.1.1
- *FARSB
[:Category:EC 6.2] (form carbon-sulfur bonds)
- : Acetate--CoA ligase
- : Medium-chain acyl-CoA ligase
- : Long-chain-fatty-acid-CoA ligase
- : Succinate-CoA ligase
- : Succinate-CoA ligase
- : Glutarate-CoA ligase
- : Cholate-CoA ligase
- : Oxalate-CoA ligase
- : Malate-CoA ligase
- : Acid-CoA ligase
- : Biotin-CoA ligase
- : 4-coumarate-CoA ligase
- : Acetate-CoA ligase
- : 6-carboxyhexanoate-CoA ligase
- : Arachidonate-CoA ligase
- : Acetoacetate-CoA ligase
- : Propionate-CoA ligase
- : Citrate-CoA ligase
- : Long-chain-fatty-acid-luciferin-component ligase
- : Long-chain-fatty-acid- ligase
- :
- : ligase
- : Dicarboxylate-CoA ligase
- : Phytanate-CoA ligase
- : Benzoate-CoA ligase
- : o-succinylbenzoate-CoA ligase
- : 4-hydroxybenzoate-CoA ligase
- : 3a,7a-dihydroxy-5b-cholestanate-CoA ligase
- :
- : Phenylacetate-CoA ligase
- : 2-furoate-CoA ligase
- : Anthranilate-CoA ligase
- : 4-chlorobenzoate-CoA ligase
- : Trans-feruloyl-CoA synthase
- :
- : 3-hydroxypropionyl-CoA synthase
- : 3-hydroxybenzoate—CoA ligase
- : acetyl-CoA synthase
- : —L-glutamate ligase
- : 4-hydroxybutyrate-CoA ligase
- : 3-propanoate-CoA ligase
- : 3-oxocholest-4-en-26-oate-CoA ligase
- : 2-hydroxy-7-methoxy-5-methyl-1-naphthoate-CoA ligase
- : 3-propionyl-CoA ligase
- : E1 ubiquitin-activating enzyme
- : L-allo-isoleucine--holo-CmaA peptidyl-carrier protein ligase
- : Medium-chain-fatty-acid- ligase
- : Carnitine-CoA ligase
- : Long-chain fatty acid adenylyltransferase FadD28
- : 4-hydroxybenzoate adenylyltransferase FadD22
- : 4-hydroxyphenylalkanoate adenylyltransferase FadD29
- : L-firefly luciferin-CoA ligase
- : L-proline-L-prolyl-carrier protein ligase
- : D-alanine-D-alanyl-carrier protein ligase
- : E1 SAMP-activating enzyme
[:Category:EC 6.3] (form carbon-nitrogen bonds)
- Glutamine synthetase
- Argininosuccinate synthetase
- CTP synthase
[:Category:EC 6.4] (form carbon-carbon bonds)
- Pyruvate carboxylase
- Acetyl-CoA carboxylase
[:Category:EC 6.5] (form [phosphoric ester] bonds)