Prince played 24 games off the bench in his freshman season. He finished the year averaging 3.7 points and 2.2 rebounds in 6.4 minutes per game. In the spring prior to his sophomore season, Prince was on the Big 12 Conference Commissioner's Honor Roll. After averaging 6.2 points and 2.8 rebounds in 14.2 minutes per game and appearing in all 38 of Baylor's games, he won the Big 12Sixth Man Award and earned all-conference honors. Entering his fourth season, Fran Fraschilla labeled him as a strong candidate for Big 12 Player of the Year in 2015–16.
Professional career
Atlanta Hawks (2016–2019)
On June 23, 2016, Prince was selected by the Utah Jazz with the 12th overall pick in the 2016 NBA draft. His rights were later traded to the Atlanta Hawks on July 7 in a three-team deal also involving the Indiana Pacers the Jazz received George Hill and the Pacers received Jeff Teague. On July 15, 2016, he signed his rookie scale contract with the Hawks. On March 11, 2017, he had a then season-best 17 points in a 107–90 win over the Memphis Grizzlies. On April 6, 2017, he scored a career-high 20 points in a 123–116 win over the Boston Celtics. With 11 points in Game 4 of the Hawks' first-round playoff series against the Washington Wizards, Prince became the first Hawks rookie to reach double-figures in his first four playoff games since Pete Maravich did it in five straight in 1971. During his rookie season, Prince had multiple assignments with the Long Island Nets of the NBA Development League, pursuant to the flexible assignment rule. On December 12, 2017, Prince scored a career-high 24 points in a 123–114 loss to the Cleveland Cavaliers. Three days later, he made a career-high five 3-pointers and had 17 points in a 96–94 loss to the Memphis Grizzlies. On December 29, 2017, he had a career-high 30 points and 10 rebounds in a 111–98 loss to the Toronto Raptors. Prince matched a career high with five 3-pointers and extended his career-high streak of games with at least one 3-pointer to 17. On February 2, 2018, he set a new career high with 31 points in a 119–110 loss to the Boston Celtics. On March 11, 2018, he set a new career high with 38 points in a 129–122 loss to the Chicago Bulls. Six days later, he had another 38-point effort in a 122–117 loss to the Milwaukee Bucks. On April 8, 2018, he made seven of eight 3-pointers to score 33 points in a 112–106 win over the Celtics. On October 19, 2018, in just the second game of the season, Prince scored a season-high 28 points against the Grizzlies. On January 13, 2019, against the Bucks, Prince returned to action after missing 18 games with a left ankle sprain.
Brooklyn Nets (2019–present)
On July 6, 2019, Prince, along with a 2021 second-round pick, was traded to the Brooklyn Nets for Allen Crabbe, the draft rights to Nickeil Alexander-Walker, and a protected 2020 first round pick. On October 21, 2019, Prince, signed a two-year $29 million extension with the Nets. Taurean Prince tested positive for Coronavirus and will sit out the Orlando restart, ESPN's Adrian Wojnarowski reports.