Serotonin receptor antagonist


A serotonin antagonist, or serotonin receptor antagonist, is a drug used to inhibit the action at serotonin receptors.

Types

5-HT2A antagonists

Antagonists of the 5-HT2A receptor are sometimes used as atypical antipsychotics.
They include, but are not limited to:
Another subclass consists of drugs selectively acting at the 5-HT3 receptors, and thus are known as 5-HT3 antagonists. They are efficacious in treating chemotherapy-induced emesis and postoperative nausea and vomiting.
They include, but are not limited to:
Other 5-HT3 antagonists are used for the treatment of irritable bowel syndrome:
Also, the antidepressant mirtazapine acts as a 5-HT3 antagonist.

Non-selective 5-HT antagonists

Please note, that although some non-selective serotonin antagonists may have a particular affinity for a specific 5-HT receptor, they still may also possess a generalised non-selective action.
They include, but are not limited to: