Histidine—tRNA ligase
In enzymology, a histidine-tRNA ligase is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, L-histidine, and tRNA, whereas its 3 products are AMP, diphosphate, and L-histidyl-tRNA.
This enzyme participates in histidine metabolism and aminoacyl-trna biosynthesis.Nomenclature
Histidine—tRNA ligase belongs to the family of ligase enzymes, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-histidine:tRNAHis ligase. Other names in common use include histidyl-tRNA synthetase, histidyl-transfer ribonucleate synthetase, and histidine translase.
