Green attended the University of Louisville from 1958 to 1961, rushing for more than 1,500 yards in his college football career with the Cardinals and twice leading the team in that department, Earning him all American honors. He also excelled in baseball, spurning contract offers in order to remain on the gridiron.
In 1962 the reigning world champion Green Bay Packers drafted Green in the 14th round of the 1962 NFL Draft, but during training camp they traded him to the Cleveland Browns where he would make a name for himself as one of the league's top running backs.
Cleveland Browns
After seeing only limited action as a rookie in 1962, Green was installed in the Cleveland backfield the following year alongside legendary Hall of FamerJim Brown. He finished his first full season of action with 526 rushing yards, and also caught 28 passes out of the backfield. Even more importantly, he also helped open holes for Brown to gain a then-NFL record 1,863 yards. In 1964, the two helped the Browns capture their fourth NFL championship, capping the year with a stunning 27-0 shutout of the Baltimore Colts at the 1964 NFL Championship Game. Following Brown's retirement in July 1966, Green was switched from halfback to fullback and teamed with another future Hall of Famer, Leroy Kelly, to continue to give Cleveland one of the most dangerous backfield combinations in the NFL. He was selected to the Pro Bowl in each of the next two seasons, and was twice named an NFL All-Pro. In August 1968, Green injured his knee during a preseason contest in Los Angeles and missed the next two months. On his return, he saw only limited action due to lingering problems with the knee. Just after the end of the season, he underwent surgery to repair torn cartilage in the troublesome knee but was then advised to retire. He followed that advice and accepted the Browns' offer to coach their running backs. In his seven-year NFL career, he gained 3,204 yards and caught 179 passes out of the backfield.
Green was diagnosed with breast cancer in July 2005 after a small malignant lump was found in his chest. After obtaining a second opinion, he was treated with mastectomyin September 2005 by Dr. Robert Schenk, breast surgeon at University Hospitals of Cleveland's Case Medical Center. This was followed by eight chemotherapy sessions ending in March 2006. He then became a breast cancer activist, educating other men about the disease and how it can affect not only women but men as well. His two older sisters were diagnosed with breast cancer, and one of them succumbed to the disease.