Frampton attended Oak Grove High School in San Jose, California, where he was an All-league selection as a junior, after rushing for 17 touchdowns. As a senior, he missed 5 games with a broken collar bone and had 30 tackles in the remaining 6 contests. He accepted a football scholarship from Washington State University. As a redshirt freshman, he played mainly on special teams, registering 8 defensive tackles in 12 games. As a sophomore, he appeared in 11 games, making 24 tackles and 3 pass breakups. He received the Washington State Ironman Award in 2004. As a junior, he became a starter at safety, registering 87 tackles, one sack, 5.5 tackles for loss, one quarterback pressure, one forced fumble, one fumble recovery, 8 pass deflections and returned one interception for a 36-yard touchdown. He made 13 tackles against USC and Arizona State University. As a senior, he was the Cougars' leading tackler and played both the free and strong safety position. He also tallied 4 tackles for loss, one sack 13 pass breakups, 2 forced fumbles and 5 interceptions with one returned for a touchdown. He made 11 tackles against USC and 16 against the University of Oregon. He finished his college career with 23-of-46 starts, 219 tackles, 6 interceptions, 2 sacks, 2 quarterback pressures and 2 touchdowns.
Professional career
Oakland Raiders
Frampton was timed at 4.61 seconds in the 40-yard dash at the 2007 NFL Scouting Combine, but improved it to 4.51 in the 40 at his College Pro Day. He was selected by the Oakland Raiders in the fifth round 2013 of the 2007 NFL Draft. He was waived before the season started on September 1, 2007.
Detroit Lions
On September 2, 2007, the Detroit Lions claimed him off waivers. He played in 5 games and had 7 special teams tackles. He was released on October 21.
Minnesota Vikings
On October 22, 2007, the Minnesota Vikings claimed him off waivers and became a special teams' standout with 14 tackles. In 2008, he was second on the team with 21 special teams takles. In 2009, he was fourth on the team with 18 special teams takles. In 2010, he was third on the team with 10 special teams tackles. In 2011, he was voted the Vikings' Special Teams MVP by his teammates, after leading the team with a career-best 22 tackles. On August 31, 2012, he was released before the season started.
Dallas Cowboys
On September 25, 2012, Frampton was signed by the Dallas Cowboys to add depth to a defense depleted by injuries. Although he played in only 13 games, he led the team in special teams tackles and was used in the team's defensive sub-packages, before being named the starter at strong safety for the last 2 games of the season. He finished the year with a career-high 21 tackles, 3 pass breakups and 2 starts on defense. He also had 25 special teams tackles, 2 passes defensed and one fumble recovery. He was re-signed on June 4, 2013. He injured his groin during training camp and was placed on the injured reserve list on September 3. He was released with an injury settlement on September 9.
