Arceneaux was signed to the BC Lions, on May 19, 2009 and made the Lions' active roster after training camp. Arceneaux had an outstanding debut season, starting at the wide receiver position for all 18 games and recording 63 catches for 858 yards and seven touchdowns. He caught a touchdown pass in each of his first three games and had two 100-yard receiving games during the season. He led all receivers in the 2009 playoffs, recording 12 catches for 189 yards. He continued his strong play in 2010 by registering his first 1000-yard season while finishing second on the team in receiving yards and touchdowns.
Minnesota Vikings
On January 22, 2011, Arceneaux agreed to the terms on a three-year contract with the Minnesota Vikings. On August 31, 2012 as the Vikings reduced their roster down to league maximum of 53 players, he was released. In his time with the Vikings Arceneaux played in three games catching one pass for 10 yards.
Washington Redskins
On September 1, 2012, the Washington Redskins claimed Arceneaux off waivers and signed him to the practice squad.
Arceneaux was signed by the New York Jets to a reserve/future contract on January 2, 2013. He was waived on May 7, 2013.
BC Lions (II)
On May 16, 2013, Arceneaux's agent announced that Emmanuel Arceneaux would be returning to CFL within a week. The BC Lions, Toronto Argonauts and Edmonton Eskimos were all believed to have interest in the free-agent. On May 21, 2013, it was officially announced that Arceneaux had signed with the Lions, with whom he had played two seasons with before going south to the NFL. The contract was reportedly a two-year, $280,000 deal. Arceneaux was fined an undisclosed amount by the CFL following a Week 4 touchdown celebration involving props. Arceneaux used the end-zone corner post and the football to mimic putting in golf. Arceneaux gained an increasingly prominent role in the Lions offense over the next three seasons, culminating in being named a CFL All-Star in 2015 after setting career highs in receptions, yards and touchdowns. Following the 2015 CFL season Arceneaux was resigned by the Lions through the 2017 CFL season. Arceneaux continued his stellar play in 2016 and 2017, catching at least 100 receptions in both seasons. On December 12, 2017 the Lions announced they had re-signed Arceneaux to a one-year deal through the 2018 season. Arceneaux suffered a torn ACL halfway through the season, at the time of the injury he was the Lions leading receiver in catches and yards.
Saskatchewan Roughriders
Arceneaux was signed to the Saskatchewan Roughriders on February 15, 2019.
