4-HO-DiPT


4-Hydroxy-N,N-diisopropyltryptamine is a synthetic psychedelic drug. It is a higher homologue of psilocin, 4-HO-DET, and is a positional isomer of 4-HO-DPT and has a tryptamine molecular sub-structure.

Dosage

4-HO-DiPT is orally active at around 3 mg and above, and its effects last for 2–3 hours. Higher doses such as those above 30 mgs can increase the duration of the effects significantly.

Effects

The effects of 4-HO-DiPT are broadly comparable to those of other serotonergic psychedelics such as LSD and psilocybin, but they are distinguished by their relative brevity. Shulgin "doubt that there is another psychedelic drug, anywhere, that can match this one for speed, for intensity, for brevity, and sensitive to dose, at least one that is active orally." An idiosyncratic effect of the drug, also noted by Shulgin, is its tendency to induce tremors.
Some users have reported a minor audio distortion with lower dosages. Higher dosages increase the polarity of the distortion. It is defined as being slightly lower in pitch and creating several different effects, such as pitch bend, volume distortion, and rate distortion. As with most DiPT psychedelics, music can become more dissonant and less harmonious. Users have also reported a visual distortion widely comparable to the hallucinogen LSD.

Pharmacology

Pharmacokinetics

Binding SitesBinding Affinity Ki
5-HT1A5.7
5-HT2A0.728
5-HT2C2.8
D1>25
D2>25
D3>25
α1A>12
α2A15
TAAR1>15
H19.8
SERT1.8
DAT>26
NET11

Legal Status

Sweden

health ministry :sv:Statens folkhälsoinstitut|Statens folkhälsoinstitut classified 4-HO-DiPT as "health hazard" under the act :sv:Lagen om förbud mot vissa hälsofarliga varor|Lagen om förbud mot vissa hälsofarliga varor as of Mar 1, 2005, in their regulation SFS 2005:26 listed as 4-hydroxi-N,N-diisopropyltryptamin , making it illegal to sell or possess.

United States

4-HO-DiPT is not scheduled at the federal level in the United States, but it is possible that it could be considered an analog of 5-MeO-DiPT, in which case purchase, sale, or possession could be prosecuted under the Federal Analog Act.

Florida

"4-Hydroxy-N,N-diisopropyltryptamine" is a Schedule I controlled substance in the state of Florida making it illegal to buy, sell, or possess in Florida.