4-HO-DET


4-HO-DET, also known as 4-hydroxy-diethyl-tryptamine, CZ-74, is a hallucinogenic drug and psychedelic compound of moderate duration. 4-HO-DET is a substituted tryptamine, structurally related to psilocin, ethocybin, and 4-HO-DIPT.

Analogs

The acetic acid ester of 4-HO-DET is known as 4-AcO-DET. The phosphoric acid ester of 4-HO-DET is known as 4-phosphoryloxy-DET, CEY-19, or ethocybin.

History

4-HO-DET received the lab code CZ-74 in the late 1950s by the inventors of the substance, Albert Hofmann and Franz Troxler. The substance was used together with its phosphoryloxy-analog ethocybin in human clinical trials in the 1960s by the German researchers Hanscarl Leuner and G. Baer.

Dosage

10-25 mg is the usual oral dosage for 4-HO-DET, while the acetate and phosphate esters are said to require a slightly higher dosage.

Effects

4-HO-DET produces entheogenic effects similar to LSD and psilocybin.

Drug prohibition laws

Sweden

health ministry :sv:Statens folkhälsoinstitut|Statens folkhälsoinstitut classified 4-HO-DET as "health hazard" under the act :sv:Lagen om förbud mot vissa hälsofarliga varor|Lagen om förbud mot vissa hälsofarliga varor as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-hydroxi-N,N-diethyltryptamin , making it illegal to sell or possess.