3'(2'),5'-bisphosphate nucleotidase


In enzymology, a 3',5'-bisphosphate nucleotidase is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are adenosine 3',5'-bisphosphate and H2O, whereas its two products are adenosine 5'-phosphate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is adenosine-3',5'-bisphosphate 3'-phosphohydrolase. Other names in common use include phosphoadenylate 3'-nucleotidase, 3'-phosphoadenylylsulfate 3'-phosphatase, phosphoadenylate 3'-nucleotidase, and 3',5'-bisphosphonucleoside 3'-phosphohydrolase. This enzyme participates in sulfur metabolism.

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes,,,,, and.