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YK-11
YK-11
is a
synthetic
steroidal
selective androgen receptor modulator
. It is a gene-selective
partial agonist
of the
androgen receptor
and does not
induce
the
physical interaction
between the
NTD/AF1
and
LBD/AF2
, which is
required
for
full
transactivation
of the
AR
. The
drug
has
anabolic
activity
in
vitro
in
C2C12
myoblasts
and
shows
greater
potency
than
dihydrotestosterone
in this
regard
.