Wesley began his career in 2006 with Santos, and was promoted to the senior side in 2007 where he played four games. In 2008, Santos sold 25% economic rights of numbers of footballer to DIS Esporte, including Wesley. Also in 2008, he started to get more playing time making 20 league appearances and 9 Copa Libertadores appearances. On 26 March 2009, Wesley joined Atlético Paranaenseon loan until the end of 2009 season. In total, he played 33 matches scoring 2 goals. In 2010, Wesley returned to Santos where he became a key player in the 2010 Campeonato Paulista and 2010 Copa do Brasil championship which team won, mostly in the right back position. On 22 May 2010, Wesley scored his first goal for Santos in a 2–1 win over Goianiense. His performances at Santos attracted interest from European clubs such as Portuguese side Benfica and German side Werder Bremen
Werder Bremen
In summer 2010, Wesley signed a four-year contract with Werder Bremen for a reported transfer fee of €7.5 million. Santos received R$ 7.735 million for its 35% economic rights with a remaining 40% of economic rights being held by unknown parties. On 11 September 2010, he made his debut in a Werder Bremen shirt in a 0–0 draw against Bayern Munich. On 23 October 2010, he scored his first goal for the club in a 4–1 win over Borussia Mönchengladbach. Wesley was kept out of action by an injury sustained in a match against Schalke 04 on 20 November 2010 before making his return on 7 March 2011 in a match against Borussia Mönchengladbach. On 20 August 2011, he scored his second goal for the club in a 5–3 win over SC Freiburg. He made a total of 26 league matches scoring 2 goals at Werder Bremen.
On 8 March2012, Wesley returned to Brazil for Palmeiras on a three-year contract for an estimated €6 million transfer fee. During the negotiations, the Brazilian club came to make a campaign to collect money through the crowd to hire the player, since it lacked the 2 million to pay the first installment of the player to the Germans. An investor willing to pay the first installment, however, allowed for the completion of the negotiations. Wesley made his debut for the club in a 1–0 loss against Paulista on 29 March 2012. On 8 April 2012, he suffered a knee ligament injury in a 3–1 loss against Guarani which kept him out of action for the rest of the season with an expected return in 2013.
