In 1884, Wabash played its first game of intercollegiate football when it defeated a team from Butler University on October 25, 4–0. The first intercollegiate game in the state took place on May 31, between Butler and DePauw University. From the 1890s to the 1910s, the Wabash football team played schedules against many much larger colleges, such as Illinois, Indiana and Purdue, against whom the Little Giants occasionally won impressive upsets. For instance Wabash won all five games against Purdue between 1906 and 1911.
Basketball
Wabash College began varsity intercollegiate competition in men's basketball in 1897. Wabash was retroactively recognized as the pre-NCAA Tournament national champion for the 1905–06 and 1907–08 seasons by the Premo-Porretta Power Poll. The 1922 National Intercollegiate Basketball Tournament was the first national championship tournament ever held in intercollegiate basketball. The 1921–22 Wabash College team won the championship game, 43–23, over Kalamazoo College. Wabash finished with a season record of 21–3, winning all three tournament games in convincing fashion. They were coached by Robert E. "Pete" Vaughan and their players were Fred Adam, Paul Schanlaub, Lon Goldsberry, John Burns, and Clyde Grater. Wabash also won the 1982 NCAA Division III championship. Coached by Mac Petty and captained by Mike Holcomb and future NFL star Pete Metzelaars, rolled their way to a 23-4 season. They were considered an inexperienced squad coming into the season. They did win their opener in Greencastle against rival DePauw in a comeback effort, 63-62. Of the four games they lost, only one was to another Division III school, Hope College, in a thrilling overtime game in Crawfordsville. The other three were to Division ILouisiana Tech and UT San Antonio and Division II Texas A&I. The team finished the year on a 19-game winning streak. Along the way, they broke Rose-Hulman's 12-game win streak, defeating the Engineers 100-51. The team received their NCAA bid the next day. They closed the regular season defeating DePauw by 10 in Crawfordsville. In the regional tournament, Wabash first met Ohio Northern and rode Metzelaars' 30 point effort to an easy 81-61 win. Next up, the Little Giants were able to avenge their only Division III loss of the season against Hope, winning 82-70. The next two games did not come so easily, squeezing out a 54-51 win against Augustana and sweating out a 68-64 win against Stanislaus State. Wabash then faced defending champion Potsdam State. The champs had no answer for Metzelaars, however, as he poured in 45 points en route to an 83-62 victory. It was the largest margin of victory in the championship at the time.