He has been actively involved in politics since he was seventeen, and in 2001 he joined the Dveri movement. In 2003, he became a member of the Elders of this movement. He was a member of the Eldership of Dveri until June 2015, when this body of the Dveri movement was abolished. He ran for president at the 2012 Serbian presidential elections and won 2.77% of the vote. After the founding assembly of the Serbian movement Dveri as a political party, held on 27 June 2015, at which the Eldership was abolished and the Transitional Council was elected and Boško Obradović was elected president of this movement. Vladan Glišić opposed such a transformation of the movement. He was not elected to any position in the movement after the Eldership was abolished. After that, Glišić withdrew from the activities in this movement and continued to criticize in the media the reforms within the movement initiated by Boško Obradović. He formally remained a member of the Dveri movement. On 15 August 2015, Dveri announced that Vladan Glišić has not spoken on behalf of this movement since the founding assembly of Dveri held on 27 June 2015, and that he can only speak on his own behalf. He was a legal advisor at the Ministry of Finance of Serbia, as well as the Deputy Public Attorney in the municipality of Rakovica. After leaving Dveri, he founded a political organization called National Network which participated in the 2016 Serbian Parliamentary election. However, the organization finished last, with only 0.46% of the popular vote. Since July 2018, he has been a member of the presidency of the newly established political party called the Serbian Patriotic Alliance, which is headed by Aleksandar Šapić. He received a fifth position at the electoral list of the Serbian Patriotic Alliance for the 2020 Serbian Parliamentary elections. After the 2020 Serbian Parliamentary elections in which the Serbian Patriotic Alliance finished third, Glisić said that his party is willing to participate in the government if the Serbian Progressive Party offers them a coalition. On 22 July 2020, Aleksandar Šapić announced that he removed Glišić from the SPAS parliamentary group and that he will also be removed from the party because he broke the party rules.
