There are several types of vascular disease,, the signs and symptoms depend on which type, among them are:
Erythromelalgia - a rare peripheral vascular disease where syndromes includes burning pain, increased temperature, erythema and swelling, of mainly the hands and feet are affected. in a 77-year-old woman |thumb
Buerger's disease – is due to small blood vessels that inflame and swell, vessels then narrow or are blocked by blood clots.
Raynaud's disease – a rare peripheral vascular disorder of constriction of the peripheral blood vessels, in the fingers and toes when the person is cold.
Cerebrovascular disease–a group of vascular diseases that affect brain function.
Mechanism
Vascular disease is a pathological state of large and medium muscular arteries and is triggered by endothelial cell dysfunction. Because of factors like pathogens, oxidizedLDL particles and other inflammatory stimuli endothelial cells become active. The process causes thickening of the vessel wall, forming a plaque that consists of proliferating smooth muscle cells, macrophages and lymphocytes. The plaque results in a restricted blood flow which will decrease the amount of oxygen and nutrients that reach certain organs, the plaque might rupture causing the formation of clots.
Diagnosis
It can be difficult to make a vascular disease diagnosis since there are a variety of symptoms that a person can have, also family history and a physical examination are important. The physical exam may be different depending on the type of vascular disease. In the case of a peripheral vascular disease the physical exam consists in checking the blood flow in the legs.
Treatment
Treatment varies with the type of vascular disease; in the case of renal artery disease, information from a meta-analysis indicated that balloon angioplasty results in improvement of diastolic blood pressure and a reduction in antihypertensive drug requirements. In the case of peripheral artery disease, preventing complications is important; without treatment, sores or gangrene may occur. Among the treatments are:
