The Boston Red Sox selected Buttrey in the fourth round of the 2012 MLB draft out of Providence High School in Charlotte, North Carolina. He had posted a 9–2 record with a 0.91 earned run average and 100 strikeouts as a senior, averaging 13.04 strikeouts per 9 innings pitched. He signed for a signing bonus of $1,300,000, forging his commitment to play college baseball at the University of Arkansas. Following four games for the Gulf Coast League Red Sox in 2012, Buttrey pitched his first full professional season in 2013 with Low-A Lowell Spinners of the New York–Penn League, where he went 4–3 with a 2.21 ERA in 13 games started. In addition, he struck out 35 batters, did not allow a home run in 61 innings and allowed over two earned runs just twice in his 13 starts. In 2014, Buttrey dealt with injuries and ineffectiveness, resulting in a 6.85 ERA with Class AGreenville Drive. He earned a promotion to High-A Lowell Spinners after a 1–0 record with a 2.45 ERA in four starts and 22 innings. He returned for Greenville to begin 2015 and was promoted to Class A AdvancedSalem Red Sox during the midseason. In his first seven starts at Salem, Buttrey went 5–0 with a 1.71 ERA in 42 innings, being unbeaten in his combined 11 starts between A and High-A in 2015. He finished with an 8–10 record in 21 starts for Salem and was a tough luck loser, as he pitched 14 quality starts, but in five of those 14 starts was charged with the loss. Overall, he went 9–10 with a 3.92 ERA in 25 starts for Greenville and Salem, including 103 strikeouts against 48 walks in 137⅔ innings. Buttrey was assigned to Double-A Portland Sea Dogs in 2016, where he struggled with his command and averaged 5.3 walks to 5.8 strikeouts per nine innings, ending with a 1–9 record and 4.50 ERA in 32 appearances. He opened 2017 at Portland and joined Triple-A Pawtucket Red Sox in the midseason. Overall, he went 2–5 with a 4.81 ERA and four saves in innings of relief duties, averaging 10.5 strikeouts per 9 innings. The Red Sox added Buttrey to their 40-man roster after the 2017 season. He started the 2018 season with Triple-A Pawtucket, for whom he was 1–1 with one save and a 2.25 ERA as he struck out 64 batters in 44 innings, averaging 13.1 strikeouts per 9 innings.
Los Angeles Angels
On July 31, 2018, the Red Sox traded Buttrey and pitcher Williams Jerez to the Los Angeles Angels for second basemanIan Kinsler. Buttrey made his MLB debut on August 16. He finished 2018 with an 0–1 record, a 3.31 ERA, and 20 strikeouts in innings. The following season, he led the team in appearances with 72, recording a win loss record of 6–7. Los Angeles Angels 2020 Ty Buttery participated in the 2020 players league for MLB The Show 20 because of the COVID-19 pandemic
