Triazolobenzodiazepine


Triazolobenzodiazepines are a class of benzodiazepine pharmaceutical drugs. Chemically, they differ from other benzodiazepines by having an additional fused triazole ring.
Examples include:
Synthesis of 1-methyltriazolobenzodiazepines is possible by heating 1,4-benzodiazepin-2-thiones with hydrazine and acetic acid in n-butanol under reflux.