Topilutamide


Topilutamide, known more commonly as fluridil and sold under the brand name Eucapil, is an antiandrogen medication which is used in the treatment of pattern hair loss in men and women. It is used as a topical medication and is applied to the scalp.
Topilutamide is a nonsteroidal antiandrogen, or an antagonist of the androgen receptor, the biological target of androgens like testosterone and dihydrotestosterone.
Topilutamide was introduced for medical use in 2003. It is marketed only in the Czech Republic and Slovakia.

Medical uses

Topilutamide is used as a topical medication in the treatment of pattern hair loss in men and women.

Available forms

As Eucapil, topilutamide is available as a 2% topical formulation intended for application to the scalp.

Pharmacology

Pharmacodynamics

Topilutamide is an antagonist of the AR, the biological target of androgens like testosterone and DHT.

Pharmacokinetics

Topilutamide is a topical medication and is applied to the scalp.

Chemistry

Topilutamide is a nonsteroidal compound and is closely related to other NSAAs such as flutamide and bicalutamide.

History

Topilutamide was introduced for medical use in 2003.

Society and culture

Generic names

Topilutamide is the generic name of the drug and its. It is also known more commonly as fluridil. Topilutamide is also known by its former developmental code name BP-766.

Brand names

Topilutamide is marketed by Interpharma Praha under the brand name Eucapil.

Availability

Topilutamide is available only in Europe in the Czech Republic and Slovakia.