Tlaxiaco is a city, and its surrounding municipality of the same name, in the Mexican state of Oaxaca. It is located in the Tlaxiaco District in the south of the Mixteca Region, with a population of about 17,450. The city is formally known as Heroica Ciudad de Tlaxiaco in honour of a battle waged there during the 1862–67 French invasion. Tlaxiaco is a Nahuatl name containing the elements tlachtli , quiahuitl , and -co . It thus approximates to "Place where it rains on the ball court". Its name in the Mixtec language is Ndijiinu, which means "good view". On January 1, 2019, Tlaxiaco found itself in the international news, when newly elected mayor, Alejandro Aparicio, was assassinated in the street shortly after taking his oath of office.
As municipal seat, Tlaxiaco has governing jurisdiction over the following communities: Agua Zarca, Arboleda, Atayiki, Barranca Obscura, Barrio San Miguel, Barrio San Nicolás, Benito Juárez Cuquila, Cañada Alejandro, Cañada Candelaria, Cañada del Curtidor, Cañada María, Cañada María, Cabayoco, Campo de Aviación, Capilla del Carrizal, Cerrito de la Virgen, Cerro Negro, Colonia Adolfo López Mateos, Cruz Llorada, Ejido Cañada Santa María, Ejido Ojo de Agua, El Apartadero, El Boquerón, El Capulín 1, El Capulín 2, El Crucero, El Mogote, El Ojite, El Sabino, El Terrero, El Vergel, Guadalupe Hidalgo, Ignacio Manuel Altamirano, Joya Grande, Juan Escutia Cuquila, Kilómetro Doce, La Angostura, La Barranca del Tabaco, La Corona, La Cruz Verde, La Desviación, La Lobera 1, La Lobera 2, La Peña Negra, La Providencia, La Purísima Concepción, La Séptima Poniente, La Unión, Las Huertas, Linda Vista 1, Linda Vista 2, Llano Castro, Llano de Guadalupe, Llano de Plaza, Llano del Guajolote, Loma Aplastado, Loma del Venado, Loma Saayii, Loma Snuviji, Los Ángeles, Los Blancos, Los Cortés, Mexicalcingo de los Granados, Mogote de San Cristóbal, Nuñuma, Nueva Reforma, Ojo de Agua 1, Ojo de Agua 2, Palo de Letra, Plan de Guadalupe, Ranchería Santos, Rancho Viejo, Rancho Viejo, Rancho Yosondua, Río de Arena, Río de los Pinos, Río de Ocotepec, Río Delgado, San Agustín Tlacotepec, San Bartolo, San Diego, San Felipe Tindaco, San Isidro, San Isidro Mirasol, San Juan de las Flores, San Miguel Progreso, San Pedro, San Pedro Llano Grande, −SAN PEDRO YOSOTATU—, San Sebastián, Santa Lucrecia, Santa María Cuquila, Santo Domingo Huendío, Snite, Tierra Azul, Tierra Blanca, Tierra Colorada, Yosobee, Yosocahanu, Yososana, Yosostato, Yosostuvi, Yosotica, Yosotium, Yucahua, Yucuhillo, Yucutu, Yutendoo, and Yutenino Segunda Sección. The municipality reported a population of 34,587 in the 2005 Census, of whom 9,399 spoke an indigenous language. The land is essentially used for habitation and small-scale agriculture, which represents the main economic activity of the municipality's inhabitants.