Bayard was born in Wilmington, Delaware, son of U.S. Senator Thomas F. Bayard Sr. and grandson of U.S. Senator James A. Bayard Jr. In 1908, he married Elizabeth Bradforddu Pont, and they had five children, Elizabeth, Thomas, Ellen, James, and Alexis. They were members of the Episcopal Church. Bayard graduated from Yale University in 1890, where he was a member of Skull and Bones, and served as secretary of his class. He attended Yale Law School and was admitted to the Delaware Bar in 1893. After living in New York City for four years and working as assistant corporation counsel, he returned to his Delaware law practice in 1901. He married Elizabeth Bradford du Pont on October 4, 1901. He had two sons Thomas Francis Bayard III Graduate of the University of Pennsylvania, Executive at the DuPont Company. Married to Ruth Broadbent Castor in 1928 in Paris, divorced in 1944. Alexis I. du Pont Bayard Graduate of Yale University, Politician and 13th Lieutenant Governor of Delaware. Married to Jane Buckley Hildreth in 1944. He died following Heart Surgery. He served as a chairman of the Delaware Democratic Party's state committee from 1906 to 1916, and as solicitor for the city of Wilmington from 1917 until 1919.
Professional and political career
Bayard was elected to the U.S. Senate in a special election on November 7, 1922, to fill the vacancy caused by the resignation of U.S. Senator Josiah O. Wolcott. On the same day, he was also elected for the full term to follow, in both instances defeating incumbent Republican U.S. Senator T. Coleman du Pont, who had been appointed. During this term, he served in the Democratic minority in the last session of the 67th Congress, and in the 68th, 69th, and 70th Congress. Bayard lost his bid for a second full term in 1928 to Republican John G. Townsend Jr., the former governor. He then lost another bid for a second full term in 1930 to incumbent Republican U.S. Senator Daniel O. Hastings. In all, Bayard served one term and part of another, from November 7, 1922, to March 3, 1929, during the administrations of U.S. presidents Warren G. Harding and Calvin Coolidge. Subsequently, he resumed his law practice in Wilmington.