The club was formed in 1868, and that year were the first opponents faced by the country's oldest club Queen's Park. From 1884, Thistle played at Beechwood Park in the Dalmarnock district of Glasgow. At the time, the area was becoming both densely populated and heavily industrialised, and several aspiring teams formed among the tenements and factories. Thistle were early rivals to Clyde whose first ground was nearby at Barrowfield Park – initially that was the home of another local club Eastern. They joined the Glasgow Football Association in 1883 and became a founder member of the Scottish Football Alliance in 1891, by which time Celtic had been formed in the neighbourhood, quickly attracting bigger crowds. In 1892 Thistle were unable to use Beechwood Park, moving to Braehead Park in the Oatlands neighbourhood. This new site was only a short distance away from the streets where their core support resided but on the opposite bank of the River Clyde; in previous and future decades it would have been easily accessible via Rutherglen Bridge at Shawfield, but the move took place between the demolition of the old bridge at that site and the completion of its replacement, making travel more difficult during those years via a temporary wooden structure. Although they had struggled in the Alliance competition, Thistle were one of the clubs invited to form the new Division Two of the Scottish League for the 1893–94 season. They failed to make an impact, suffering some heavy defeats, including a 13–1 reverse at fellow new entrants Partick Thistle on 10 March 1894, the largest defeat in the Scottish League up to that point; it has only been exceeded by Dundee Wanderers' 15–1 loss to Airdrieonians the following season. Thistle had beaten their Partick namesakes 6–2 in the Alliance League in October 1892, but by the time they first met in the SFL, Braehead Park was said to have been in a state of disrepair and its team was struggling financially, although in that match the score was only Thistle 3–4 Partick Thistle. Finishing bottom of the league, the club folded before the re-election meeting, despite takings of £118 at a benefit match between Sunderland and a Scottish Football League XI. Their final fixture was a friendly against Clyde. A group of Thistle supporters almost immediately formed a new club, Strathclyde F.C., named after the street where Beechwood Park stood. They entered the Junior setup, initially playing back in Dalmarnock at New Beechwood Park and eventually settling at New Springfield Park ; they won the Scottish Junior Cup three times before eventually folding in the 1960s.
