The Hippocratic Crush II immediately follows off from The Hippocratic Crush, following the lives of doctors, new and old, facing the patients and challenges that unfold before them. Cheung Yat Kin/Yat Kin Tau and Fan Chi Yu are now happily married to each other but life ahead is not easy for them. They are faced with new obstacles that they have to face together if they are to keep their relationship growing strong. Chi Yu finds herself pregnant but being diagnosed with intramedullary spinal cord tumour makes her unfit to continue with the pregnancy. However, she insists on carrying on with the pregnancy and this causes disputes between the couple. Though this does not mean that Yat Kin loves Chi Yu any less; he just can’t bear watching her suffer so he offers to carry some of her burdens. The challenges that he has to face with Yu Zai on top of his stubborn personality takes a toll on his relationship with newly transferred pathology specialist, Lok Man San/Lokman. The two are constantly at each other’s head with differing opinions and their different approach with medicine further causes tension between the two doctors. Lokman gets involved with fellow internal medicine doctor, Heung Chin Yi, who is twenty years his junior. Lokman and Chin Yi have a very different view of love. Lokman is a widowed man with a young daughter while Chin Yi is left having to take care of her runaway boyfriend's son. Through mutual understanding and hardships, the two grow to love each other despite their age difference. Yu Zai’s illness causes her to eventually relent to getting an abortion, as well as making her incompetent to perform surgery on patients. This is a huge blow to her as well as Yat Kin Tau. His mother also falls sick and this added on to all the pressure in life causes him to develop an anxiety disorder. However, with Yat Kin Tau by her side, Yu Zai isn’t ready to give up yet; she wants to help Yat Kin Tau to stand strong again. So she decides to switch afresh, switching from cardiology to pathology, learning under the disciplinary of Lokman who helps her to regain her strength. Meanwhile, Yu Zai’s sister and neurosurgeon, Hong Mei Suet also has her own challenges to face as she finally becomes a doctor in her own right. However, that is not the only challenge in her life. Her relationship with orthopaedic surgeon boyfriend Lau Ping Chan/Benjamin heads on the rocks as their relationship turns into a love triangle. Fresh Cardiosurgeon, Yeung Pui Chung undergoes his own journey to become a better doctor. As his career picks up, he finds himself in a love triangle with training doctor, Zung Zi Ting and social worker, Ce Hui Tung who suffers from a chronic illness. Yat Kin Tau finds it difficult to accept the new challenges in his life, however, as he watches his friends and fellow subordinates, Mei Suet and Pui Chung grow to become independent, capable and experienced doctors, he learns that he must first protect himself before he can protect others. Will he be able to do this and protect those whom he loves and cares about? What is the true meaning behind being a doctor? It is merely about saving about patients? What about the doctors themselves?
