TNIK


TRAF2 and NCK-interacting protein kinase is an enzyme that in humans is encoded by the TNIK gene.

Function

Germinal center kinases, such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function.

Interactions

TNIK has been shown to interact with KIAA0090, although the significance is unclear. TNIK has been shown to phosphorylate Gelsolin, a protein involved in F-actin depolymerisation thus inducing cytoskeletal changes.