TIP39


Tuberoinfundibular peptide of 39 residues is a protein that in humans is encoded by the PTH2 gene.
TIP39 is related to parathyroid hormone and PTH-related protein and is a ligand for PTH receptor-2 .
The molecular interaction of TIP39 with the PTH2 receptor has been characterized in full 3D molecular detail, identifying among other residues, Tyr-318 in transmembrane helix 5 as a key residue for high affinity binding