Sydenham
- Charles Poulett Thomson, 1st Baron Sydenham
- Colonel William Sydenham
- John Sydenham (disambiguation)
- Lower Sydenham railway station
- Owen Sound
- Sunbury railway line
- Sydenham (New Zealand electorate)
- Sydenham College
- Sydenham Damerel
- Sydenham Elnathan Ancona
- Sydenham High School
- Sydenham Hill railway station
- Sydenham Hospital
- Sydenham Hospital for Communicable Diseases
- Sydenham House
- Sydenham House, Devon
- Sydenham River (Lake Huron)
- Sydenham River (Lake Saint Clair)
- Sydenham School
- Sydenham Ward
- Sydenham railway station (Belfast)
- Sydenham railway station (London)
- Sydenham railway station (disambiguation)
- Sydenham railway station, Sydney
- Sydenham's chorea
- Sydenham, Belfast
- Sydenham, Durban
- Sydenham, Frontenac County, Ontario
- Sydenham, Gauteng
- Sydenham, Grey County, Ontario
- Sydenham, London
- Sydenham, New South Wales
- Sydenham, New Zealand
- Sydenham, Oxfordshire
- Sydenham, Port Elizabeth
- Sydenham, Somerset
- Sydenham, Victoria
- Sydenham, Warwickshire
- Thomas Sydenham
- Watergardens railway station