Swimming at the 2016 Summer Paralympics – Women's 100 metre freestyle S6
The women's 100 metre freestyle S6 event at the 2016 Paralympic Games took place on 17 September 2016, at the Olympic Aquatics Stadium. Three heats were held. The swimmers with the eight fastest times advanced to the final.Heats
9:40 17 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 1 | 5 | | | 1:16.76 | ' |
| 2 | 4 | | | 1:17.75 | ' |
| 3 | 3 | | | 1:23.46 | |
| 4 | 2 | | | 1:23.88 | |
| 5 | 7 | | | 1:25.89 | |
Heat 2
9:45 17 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 1 | 4 | | | 1:15.04 | ' |
| 2 | 5 | | | 1:18.50 | ' |
| 3 | 6 | | | 1:22.39 | |
| 4 | 7 | | | 1:27.02 | |
| 5 | 2 | | | 1:27.04 | |
| 6 | 1 | | | 3:11.76 | |
Heat 3
9:48 17 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 1 | 4 | | | 1:12.49 | ' ' |
| 2 | 5 | | | 1:16.39 | ' |
| 3 | 3 | | | 1:20.15 | ' |
| 4 | 6 | | | 1:24.32 | |
| 5 | 2 | | | 1:24.78 | |
| 6 | 1 | | | 1:27.88 | |
Final
17:36 17 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 4 | | | 1:11.40 | |
| 5 | | | 1:13.47 | |
| 6 | | | 1:14.43 | |
| 4 | 7 | | | 1:14.46 | |
| 5 | 3 | | | 1:15.77 | |
| 6 | 2 | | | 1:17.56 | |
| 7 | 1 | | | 1:18.34 | |
| 8 | 8 | | | 1:22.05 | |
