Swimming at the 2007 Pan American Games – Women's 4 × 100 metre freestyle relay
The Women's 4x100m Freestyle Relay event at the 2007 Pan American Games took place at the Maria Lenk Aquatic Park in Rio de Janeiro, Brazil, with the final being swum on July 19.
Medalists
Results
Finals
Preliminaries
The heats was held on July 18.| Place | Country | Swimmers | Time | Note |
| 1 | Lauren Thies Emily Kukors Maritza Correia Michele King | 3:45.76 | Q | |
| 2 | Hilary Bell Chanelle Charron-Watson Elizabeth Collins Seanna Mitchell | 3:47.18 | Q | |
| 3 | Tatiana Lemos Flávia Delaroli Monique Ferreira Manuella Lyrio | 3:54.25 | Q | |
| 4 | Nikia Deveaux Alana Dillette Arianna Vanderpool-Wallace Ariel Weech | 3:54.99 | Q | |
| 5 | Ximena Vilar Yanel Pinto Jeserick Pinto Jennifer Marquez | 3:59.42 | Q | |
| 6 | Liliana Ibañez Alma Arciniega Sandra Alanis Mariana Alvarado | 3:59.48 | Q | |
| 7 | Antonella Scanavino Elsa Pumar Ines Remersaro Andrea Guerra | 4:10.30 | Q | |
| 8 | María Torres Fiorella Gómez Sánchez Valeria Silva Massie Carrillo | 4:13.67 | Q | |
| 9 | Sharon Fajardo Laura Leiva Karen Poujol Laura Páz | 4:19.75 |