Sodium trichloroacetate
Sodium trichloroacetate is a chemical compound with a formula of CCl3CO2Na. It is used to increase sensitivity and precision during transcript mapping.Preparation
Sodium trichloroacetate is made by reaction trichloroacetic acid with sodium hydroxide:Reactions
Basicity
Compared to sodium acetate, The basicity of sodium trichloroacetate is weaker because of the electron-withdrawing nature of the trichloromethyl group. Sodium trifluoroacetate is an even weaker base than that due to higher electronegativity of fluorine atoms. In the presence of strong acids the anion can be protonated:
