Faults in the 1964 Wilderness Act made it essentially impossible to designate a wilderness area anywhere east of the Mississippi River. Mary Ivy Burks of Birmingham worked to establish a Sipsey Wilderness Area in the Bankhead National Forest at a time when many believed that "The Wilderness Act" should apply only to the western part of the United States. She was in the forefront of what became known as the Eastern Wilderness Movement. Her work to secure the Sipsey Wilderness in the Bankhead National Forest was her crowning achievement. John Randolph and Mike Leonard led the effort to expand the wilderness in a second phase during the 1980s. Alabama would be the agent of change, as a strange union of environmentalists, loggers, bird watchers, and others joined together to push to change the Act to allow for the designation of Sipsey as a wilderness area. Thanks to a bill introduced by Senator John Sparkman, the Eastern Wilderness Areas Act of 1975, the wilderness was finally designated with an original size of. The wilderness would be expanded in 1988. Thanks to the changes made to the Act, dozens of wilderness areas have been designated across the United States. The Sipsey Wilderness helped to show that a smaller plot of restored land in the eastern US could be a wilderness just as much as a larger tract of virgin land in the west.
Trail maps are available from the , and from . During the 2011 Super Outbreak of tornadoes, there was extensive damage to much of the north Sipsey area. It was not considered feasible to fully repair the trail system at the time and efforts were focused on more popular routes. Several badly damaged trails were considered "abandoned" indefinitely, pending the resources to clear them. There is a notice to this effect placarded at the main Sipsey Trailhead, however this notice is not always present at outlying trailheads. It appears that more recently some effort to clear and reroute the remainder of these trails has started taking place, although it is limited and trail reports continue to suggest difficulty hiking and following some less common trails. It is suggested that potential hikers find reliable recent information while planning a hike.
Places of interest
Saltpeter Furnace: Located not far from the Bee Branches, a small cave is hidden by a waterfall, and that cave was once so important that a small skirmish was fought at the nearby Hubbard's cotton mill during the American Civil War. The cave is a source of saltpeter, a major ingredient in the manufacture of gunpowder.
Sipsey River Picnic Area: Where Cranal Road crosses the Sipsey River, a day-use area has been constructed to allow for picnicking and to serve as a parking area for hiking in the area. A $3 per vehicle day use fee is charged.