student Prince Alexis is accused of stealing the athletic funds. Friend and fellow student Watson recommends he seek the assistance of classmate Sherlock Holmes. Meanwhile, while honing his observational skills out in the countryside, Holmes falls and is knocked unconscious. A young woman passerby, Alice Faulkner, comes to his aid, much to his delight. Holmes accepts the case, and soon has a suspect, Forman Wells. Wells eventually confesses he took the money to try to get away from Moriarty ; Wells is actually the son of a crook being groomed by the criminal mastermind for some later scheme. Fascinated, Holmes meets Moriarty face to face, impudently asking to study him, but of course Moriarty refuses to cooperate. Holmes informs Watson he has found his mission in life: to stop Moriarty. Meanwhile, Alexis's uncle, Count von Stalburg, arrives with important news: both his brothers have been killed in a "motor accident". He is now the Crown Prince, and as such, cannot marry Rose Faulkner, Alice's sister. Heartbroken, Rose commits suicide. Years pass. Holmes is praised in a newspaper for solving a mystery that baffled Scotland Yard. His investigative skills have failed to locate Alice Faulkner, but their paths do cross again. Moriarty is after Rose Faulkner's love letters from the Prince for blackmail. He has had her destitute sister Alice hired as a secretary by "G. Neville Chetwood", actually a henchman named James Larrabee. When the Prince asks Holmes to take the case, he initially refuses, as he holds the Prince responsible for Rose's death, but changes his mind when he learns that Alice is involved. Holmes has Forman Wells infiltrate the Larrabee household as the new butler. Through trickery, Holmes gets Alice to reveal where she has hidden the letters, but oddly, once he has them in his hands, returns them to her, even though she intends to publish them to avenge her sister. He informs Watson that the letters will be the bait to lure Moriarty out of his lair. For his part, Moriarty has become frustrated at being driven further and further underground by Holmes' relentless pursuit of him. He has Alice brought to a "gas chamber". Holmes walks knowingly into the trap, but manages to rescue Alice anyway. Moriarty then sets his entire vast organization in motion to try to kill his nemesis. Holmes is up to the challenge, however. Most of Moriarty's henchmen are captured by the police, and when Moriarty comes in person to do the job, Holmes nabs him too. Holmes then plans his honeymoon with Alice.
Material held by Eastman House was the basis for a reconstruction produced by Kevin Brownlow and William K. Everson, with a second reconstruction undertaken by Eastman House itself in 2001. Describing the first reconstruction attempt in 1975, Everson made it clear that reassembling the available material into a viewable form was a far from trivial task: "A few years ago all that existed of this film were rolls and rolls of negative sections, in which every take--not every sequence, but every take--were jumbled out of order, with only a few flash titles for guidance and a script that in many ways differed from the play, adding to the herculean task of putting it all together." The 2001 reconstruction was released on DVD by Kino International in 2009, with about 26 minutes of footage still missing. A Kino Blu-ray release followed in December 2011.