The church was built no later than the 8th century above the ruins of a Roman structure, the Portico of Livia. According to the tradition, the first church was built under Pope Symmachus back in the 6th century. The building was restored by Pope Honorius I in the 7th century and again by Pope Leo III in the 9th century. The deaconry of Saint Lucy in Silice created around 300 is one of the seven original deaconries in Rome. It was confirmed by Pope Saint Sylvester I ca. 314. The church was restored by Pope Honorius I ca 630 in the vicinity of the monumental fountain lacus orphei. It was assigned to one of the seven deacons by Pope Agatho ca. 678. According to Liber Pontificalis, this deaconry received donations from Pope Leo III. After the 10th century it was known as Santa Lucia in Silice or in Selci because it was decorated with large flintstones. The deaconry was suppressed in 1587 by Pope Sixtus V. In the 13th century, a monastery was attached to the church, enclosing it. In 1370, it was granted to the Carthusians. In 1534, it was given to the Benedictines, and in 1568 Pope Pius V granted it to the Augustinians, who still serve the church. Pope Urban VIII altered the monastery in 1624, enlarging it and dividing it into three parts. One was kept by the Augustinians, one was given to Dominican friars and the last was given to the Poor Clares. The monastery was amplified in 1603 according to designs by Bartolomeo Bassi, active in Rome at that time. However, all that remains of this amplification is the portal of the exterior. In 1878 the Italian state expropriated the convent of the Poor Clares, adjacent to San Lorenzo in Panisperna, but the nuns came to the monastery of Santa Lucia in Selci. Carlo Maderno reconstructed the church in 1604, keeping it enclosed within the Augustinian monastery. The interior of the church was refurbished in 1637-1638 by Francesco Borromini.
Interior
The church is built on a rectangular ground plan and barrel vault. It has a single nave with three shallow chapels on each side. The barrel vault has a 19th-century fresco by an unknown artist that replaced one with the same motif by Giovanni Antonio Lelli, depicting the Glory of St Lucy. The counterfaçade is decorated with the painting God the Father by Cavaliere d'Arpino. The high altar dates from the 19th century, and replaces one made by Borromini. The painting above the high altar depicting the Annunciation is a work of the Florentine painter Anastasio Fontebuoni. The Landi Chapel, commissioned by the prioress Vittoria Landi, is the first chapel on the left. It was decorated by Borromini, and the altarpiece depicts The Holy Trinity with Saint Augustine and Saint Monica by Cavaliere d'Arpino. The Chapel of the Blessed Sacrament, the second on the left, contains works attributed to Carlo Maderno: a tabernacle in polychrome marble and gilt bronze and the alabaster statues. At the first altarpiece on the right depicts Martyrdom of St Lucy by Giovanni Lanfranco. The Vision of St Augustine by Andrea Camassei is at the second altar on the right. In the choir, attributed to Francesco Borromini, several paintings by Baccio Ciarpi are displayed.
