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Salicylanilide
Salicylanilide
is a
chemical compound
which is the
amide
of
salicylic acid
and
aniline
. It is
classified
as both a
salicylamide
and an
anilide
.
Derivatives
of salicylanilide have a
variety
of
pharmacological
uses.
Chlorinated
derivatives
including
niclosamide
,
oxyclozanide
, and
rafoxanide
are used as
anthelmintics
, especially as
flukicides
.
Brominated
derivatives including
dibromsalan
,
metabromsalan
, and
tribromsalan
are used as
disinfectants
with
antibacterial
and
antifungal
activities
.
Uses
Salicylanilides may be used as
antiseptics
.
Replacement
of the
phenol
with
iodo
leads
to :de:Benodanil, which is
fungicidal
.