List of highways numbered 116

• A116 (disambiguation)
• Alabama State Route 116
• Arkansas Highway 116
• Arkansas Highway 116 (1927)
• BR-116
• California State Route 116
• Colorado State Highway 116
• Connecticut Route 116
• County Road 116 (Duval County, Florida)
• County Route 116 (Bergen County, New Jersey)
• County Route 116 (Fulton County, New York)
• County Route 116 (Niagara County, New York)
• County Route 116 (Rensselaer County, New York)
• County Route 116 (Suffolk County, New York)
• County Route 116 (Sullivan County, New York)
• County Route 116A (Fulton County, New York)
• D116 road
• Farm to Market Road 116
• Florida State Road 116
• Georgia State Route 116
• Illinois Route 116
• Indiana State Road 116
• Iowa Highway 116
• K-116 (Kansas highway)
• Louisiana Highway 116
• M-116 (Michigan highway)
• Maine State Route 116
• Maryland Route 116
• Massachusetts Route 116
• Minnesota State Highway 116 (1934–1955)
• Minnesota State Highway 116 (1965–1976)
• Missouri Route 116
• National Highway 116 (India)
• National Route 116 (Costa Rica)
• Nebraska Highway 116
• Nevada State Route 116
• New Brunswick Route 116
• New Hampshire Route 116
• New Mexico State Road 116
• New York State Route 116
• North Carolina Highway 116
• Ohio State Route 116
• Oklahoma State Highway 116
• P116
• Pennsylvania Route 116
• Prince Edward Island Route 116
• Puerto Rico Highway 116
• Puerto Rico Highway 116R
• Quebec Route 116
• R116 road (Ireland)
• Rhode Island Route 116
• Route 116 (Japan)
• S116 (Amsterdam)
• South Carolina Highway 116
• South Dakota Highway 116
• Tennessee State Route 116
• Texas State Highway 116
• Texas State Highway Loop 116
• Texas State Highway Spur 116
• U.S. Route 116
• U.S. Route 116 (Wisconsin)
• Utah State Route 116
• Vermont Route 116
• Virginia State Route 116
• Virginia State Route 116 (1923-1928)
• Virginia State Route 116 (1928-1930)
• Virginia State Route 116 (1930-1932)
• Washington State Route 116
• Wisconsin Highway 116
• Wyoming Highway 116