Franklin grew up in Hazelhurst, Mississippi. His mother allowed him to play sports in school as long as he also agreed to take voice lessons. His family moved to Oxford, Mississippi when he was 14. He suffered a head injury in high school that resulted in the formation of a blood clot that ended his football career and made him ineligible for the military. Around the same time he found work as a teen disc jockey, which got him interested in combining his interests in broadcasting and sports. While a student at the University of Mississippi, Franklin worked the wake-up shift at a radio station, attended classes during the day, and then returned to the station in the evening to work on commercials. For further vocal training, he performed in college theater. He is an alumni member of Sigma Alpha Epsilon fraternity. Prior to ESPN, he was basketball and football play-by-play commentator for the University of Texas from 1983 to 1988. He was the play-by-play voice of the Houston Oilers from 1977 to 1982. He also worked as sports director for four different local news stations: KSWS-TV in Roswell, New Mexico in 1965, KVOO-TV in Tulsa, Oklahoma from 1967 to 1971, and in Houston, Texas with KHOU-TV from 1971 to 1980, then with KPRC-TV from 1980 to 1987.
On October 1, 2005, during a game between Notre Dame and Purdue that Franklin was calling, sideline reporter Holly Rowe praised Purdue defensive coordinatorBrock Spack for using all three timeouts on defense despite trailing by four touchdowns late in the game. "If the coaches are giving up," Rowe added, "What does that say to the players?" Franklin responded, "Holly, it's not giving up. It's 49–21, sweetheart." In response to that, Mo Davenport, senior coordinating producer for college football said, "It was an inappropriate comment, and we've communicated that to Ron. There's never a reason to say something so mean-spirited. Ron apologized. We dealt with it internally."
During a production meeting prior to ESPN's telecast of the Chick-fil-A Bowl on December 31, 2010, Franklin addressed sideline reporter Jeannine Edwards in a condescending tone as "sweet baby"; when she objected, Franklin called her an "asshole". The incident was reported to ESPN by another colleague, and ESPN tried to pull Franklin from the Chick Fil-A coverage that night but was unable; instead, Franklin was removed from ESPN Radio's coverage of the 2011 Fiesta Bowl the following day. Franklin apologized for his remarks the following Monday and said he deserved to be pulled from the Fiesta Bowl. However, ESPN fired Franklin the following day; in a statement, ESPN noted, "Based on what occurred last Friday, we have ended our relationship with him."
Personal life
Franklin is married with one child. He lives in Austin, Texas.