When his father died shortly before 20 May 1420 while campaigning in France, Ralph Neville became heir apparent to his grandfather, Ralph Neville, 1st Earl of Westmorland. He succeeded to the earldom in 1425, but spent much of the rest of his life attempting to recover his inheritance, which his grandfather, the 1st Earl, had settled on his second wife, Lady Joan Beaufort, the legitimated daughter of John of Gaunt and the children he had had by her, giving rise to the Neville–Neville feud. In 1426, Westmorland had licence to enter his lands, and on 14 May of that year was knighted by King Henry VI. In the same year he married Elizabeth Percy, the daughter of Sir Henry Percy, KG, and widow of John Clifford, 7th Baron Clifford. They had one son, Sir John Neville, who married his cousin Lady Anne Holland, the daughter of John Holland, 2nd Duke of Exeter, and died without issue shortly before 16 March 1450. Westmorland married secondly, before February 1442, Margaret Cobham, 4th Baroness Cobham, daughter and heiress of Reginald Cobham, 3rd Baron Sterborough, 3rd Lord Cobham, and sister-in-law of Humphrey, Duke of Gloucester. By her he had one daughter, Margaret, who died young. As noted, Westmorland was involved in an ongoing struggle, sometimes violent, to regain his inheritance from his grandfather's second wife, Lady Joan Beaufort, and his half-uncle Richard Neville, 5th Earl of Salisbury, Cardinal Henry Beaufort, and Thomas Langley, Bishop of Durham. Lady Joan Beaufort died in 1440, and eventually a settlement was reached in 1443 which, according to Pollard, represented a 'crushing defeat' for Neville, who regained the barony of Raby but was forced to concede the rest of the disputed lands to Salisbury. Westmorland was appointed a Commissioner of Array in 1459 and 1461, and is said to have led troops raised in his name on the Lancastrian side in Durham in November 1460, but otherwise took little part in the military campaigns or political affairs of the day, and according to Pollard had by this time 'succumbed to a mental disorder', and been placed under the guardianship of his brother, Sir Thomas Neville. Westmorland's two brothers gained some influence in the late 1450s, but the death of his brother John at the Battle of Towton and his subsequent attainder on 4 November 1461 put an end to any renewed hope of the recovery of Westmorland's inheritance. Sir Humphrey Neville, son and heir of Westmorland's brother, Sir Thomas, took up the cause for a time against his cousin Richard Neville, 16th Earl of Warwick, the 'Kingmaker', who championed the position taken earlier by the Beauforts, but Humphrey was beheaded on 29 September 1469. According to Pollard, it is unclear who, if anyone, became Westmorland's guardian after the death of his brother, Sir Thomas Neville; however surviving documents indicate that Richard, Duke of Gloucester, the future Richard III, acquired an interest in Westmorland's estates, and occasionally used Raby Castle as his own residence.
Death
Westmorland died 3 November 1484, and was buried at St. Brandon's church, Brancepeth, Durham. He was predeceased by his second wife, Margaret, who died between 20 November 1466 and 26 April 1471, and was buried in the church of the Greyfriars, Doncaster. Westmorland was succeeded in the earldom by his nephew, Ralph Neville.
