Cast of ER
ER is an American drama series that aired on NBC from September 19, 1994 until April 2, 2009. The series featured a large ensemble cast that changed dramatically over its long run. The main cast was augmented by a wealth of recurring characters and award-winning guest stars.
Main cast
The original starring cast consisted of Anthony Edwards as Dr. Mark Greene, George Clooney as Dr. Douglas "Doug" Ross, Sherry Stringfield as Dr. Susan Lewis, Noah Wyle as medical student John Carter, and Eriq La Salle as Dr. Peter Benton. Julianna Margulies guest starred in the pilot as Nurse Carol Hathaway before becoming part of the regular cast.The first additions to the main cast came in Season 2 with Gloria Reuben signing on as Physician Assistant Jeanie Boulet, and in Season 3 with Laura Innes as Dr. Kerry Weaver. In Season 4, Maria Bello signed on as Dr. Anna Del Amico and Alex Kingston joined the cast as Dr. Elizabeth Corday. Season 5 saw the addition of Kellie Martin as medical student Lucy Knight.
George Clooney's departure towards the end of Season 5 started a major cycle of main cast changes over the next few years. Season 6 opened with the addition of Paul McCrane as Dr. Robert "Rocket" Romano, Croatian actor Goran Visnjic as Dr. Luka Kovač, and Michael Michele as Dr. Cleo Finch. A bit later in the season Erik Palladino joined as Dr. Dave Malucci, and Ming-Na returned to the series as Dr. Jing-Mei "Deb" Chen, reprising a recurring character she portrayed in Season 1. Soon after, Maura Tierney was added as Nurse Abigail "Abby" Lockhart. Season 8 saw the arrival of Sharif Atkins as medical student Michael Gallant, as well as the return of Dr. Susan Lewis when Sherry Stringfield reprised her role after having left the series in Season 3.
Mekhi Phifer joined the cast in Season 9 as Dr. Gregory "Greg" Pratt. Season 10 saw the addition of Parminder Nagra as medical student Neela Rasgotra and Linda Cardellini as Samantha "Sam" Taggart. Shane West joined the cast in Season 11 as Ray Barnett and Scott Grimes became part of the main cast in Season 12 as Dr. Archie Morris. Season 13 saw the addition of John Stamos as Dr. Tony Gates, reprising a role he had originated in Season 12 when he portrayed Gates the paramedic/medical student. Season 15 saw the final additions to the main cast, with David Lyons signing on as Dr. Simon Brenner and Angela Bassett as Dr. Catherine "Cate" Banfield.
Notably, of the 26 main cast members that starred throughout ER's 15-season run, only seven were not featured in the final season: Gloria Reuben, Maria Bello, Kellie Martin, Michael Michele, Erik Palladino, Ming-Na, and Sharif Atkins. In addition, only four main cast members never made a return appearance of any type following their original stint: Maria Bello, Kellie Martin, Erik Palladino, and Mekhi Phifer.
Main characters
Timeline of County General Staff
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Alignbars = justify
DateFormat = mm/dd/yyyy
Period = from:09/19/1994 till:05/01/2009
TimeAxis = orientation:horizontal format:mm/dd/yyyy
ScaleMajor = unit:year increment:1 start:1995
ScaleMinor = unit:year increment:1 start:09/20/1994
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at:04/02/2009 color:black layer:back width:0.1
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bar:carter text:"John Carter"
bar:ross text:"Doug Ross"
bar:lewis text:"Susan Lewis"
bar:greene text:"Mark Greene"
bar:chen text:"Jing-Mei 'Deb' Chen"
bar:tracy text:"Harper Tracy"
bar:doyle text:"Maggie Doyle"
bar:delamico text:"Anna Del Amico"
bar:henry text:"George Henry"
bar:west text:"Ellis West"
bar:knight text:"Lucy Knight"
bar:lee text:"Amanda Lee"
bar:finch text:"Cleo Finch"
bar:malucci text:"Dave Malucci"
bar:kovac text:"Luka Kovac"
bar:lawrence text:"Gabe Lawrence"
bar:lockhart text:"Abby Lockhart"
bar:gallant text:"Michael Gallant"
bar:pratt text:"Greg Pratt"
bar:harkins text:"Erin Harkins"
bar:nathan text:"Paul Nathan"
bar:rasgotra text:"Neela Rasgotra"
bar:morris text:"Archie Morris"
bar:cooper text:"Nick Cooper"
bar:lester text:"Lester Kertzenstein"
bar:barnett text:"Ray Barnett"
bar:howard text:"Howard Ritzke"
bar:penny text:"Penny Nicholson"
bar:figler text:"Jane Figler"
bar:scanlon text:"Jake Scanlon"
bar:clemente text:"Victor Clemente"
bar:gates text:"Tony Gates"
bar:hope text:"Hope Bobeck"
bar:katey text:"Katey Alvaro"
bar:maeleepark text:"Mae Lee Park"
bar:larryweston text:"Larry Weston"
bar:moretti text:"Kevin Moretti"
bar:grady text:"Paul Grady"
bar:zelinsky text:"Harold Zelinsky"
bar:skyewexler text:"Skye Wexler"
bar:brenner text:"Simon Brenner"
bar:lavernestjohn text:"Laverne St. John"
bar:kayamontoya text:"Kaya Montoya"
bar:banfield text:"Catherine Banfield"
bar:tracymartin text:"Tracy Martin"
bar:andrewwade text:"Andrew Wade"
bar:dariawade text:"Daria Wade"
bar:ryansanchez text:"Ryan Sanchez"
bar:chazpratt text:"Chaz Pratt"
bar:juliawise text:"Julia Wise"
bar:benton text:"Peter Benton"
bar:hicks text:"Angela Hicks"
bar:edson text:"Dale Edson"
bar:gant text:"Dennis Gant"
bar:keaton text:"Abby Keaton"
bar:corday text:"Elizabeth Corday"
bar:dorset text:"Eddie Dorset"
bar:lawson text:"Jeremy Lawson"
bar:dubenko text:"Lucien Dubenko"
bar:albright text:"Jessica Albright"
bar:crenshaw text:"Dustin Crenshaw"
bar:grossman text:"Barry Grossman"
bar:morgenstern text:"David Morgenstern"
bar:swift text:"William Swift"
bar:weaver text:"Kerry Weaver"
bar:anspaugh text:"Donald Anspaugh"
bar:romano text:"Robert Romano"
bar:hathaway text:"Carol Hathaway"
bar:haleh text:"Haleh Adams"
bar:malik text:"Malik McGrath"
bar:lydia text:"Lydia Wright"
bar:conni text:"Conni Oligario"
bar:wendy text:"Wendy Goldman"
bar:lily text:"Lily Jarvik"
bar:chuny text:"Chuny Marquez"
bar:yosh text:"Yosh Takata"
bar:LynetteEvans text:"Lynette Evans"
bar:sam text:"Samantha Taggart"
bar:inez text:"Inez"
bar:evepayton text:"Eve Payton"
bar:dawn text:"Dawn Archer"
bar:benparker text:"Ben Parker"
bar:suri text:"Suri"
bar:boulet text:"Jeanie Boulet"
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bar:season at:09/30/1999 text:Six
bar:season at:10/12/2000 text:Seven
bar:season at:09/27/2001 text:Eight
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bar:season at:09/25/2003 text:Ten
bar:season at:09/23/2004 text:Eleven
bar:season at:09/22/2005 text:Twelve
bar:season at:09/21/2006 text:Thirteen
bar:season at:09/27/2007 text:Fourteen
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bar:brenner from:04/10/2008 till:04/02/2009 color:erattend
bar:carter from:02/14/2009 till:04/02/2009 color:erattend
bar:gates from:09/27/2007 till:04/02/2009 color:doc
bar:grady from:10/09/2008 till:03/19/2009 color:doc
bar:juliawise from:04/02/2009 till:04/02/2009 color:intern
bar:tracymartin from:10/09/2008 till:04/02/2009 color:intern
bar:andrewwade from:10/09/2008 till:03/19/2009 color:intern
bar:dariawade from:10/09/2008 till:03/12/2009 color:intern
bar:ryansanchez from:10/09/2008 till:04/02/2009 color:intern
bar:kayamontoya from:10/09/2008 till:12/04/2008 color:intern
bar:lavernestjohn from:10/09/2008 till:04/02/2009 color:intern
bar:chazpratt from:11/06/2008 till:03/12/2009 color:student
bar:dubenko from:10/16/2008 till:03/26/2009 color:schief
bar:anspaugh from:09/22/2006 till:04/02/2009 color:chief
bar:sam from:10/30/2003 till:04/02/2009 color:nurse
bar:haleh from:11/17/2005 till:04/02/2009 color:nurse
bar:haleh from:10/09/2008 till:04/02/2009 color:chargenurse width:3
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bar:suri from:04/19/2007 till:04/02/2009 color:nurse
bar:lydia from:04/02/2009 till:04/02/2009 color:nurse
Departures from the main cast
's first departure from the show was in 1996, when her character, Susan Lewis, moved to Phoenix, Arizona, in the Season 3 episode "Union Station." In 2001, Stringfield returned to the series, reprising her role of Dr. Lewis, in the Season 8 episode "Never Say Never." She departed again in the Season 12 premiere, "Canon City." This departure was not depicted, but rather mentioned by character Kerry Weaver four episodes later in "Wake Up," when she explains that Susan accepted a tenure-track position at a hospital in Iowa City, Iowa, after being denied tenure at County. Stringfield returned once again for the series finale.After playing Anna Del Amico for one season, Maria Bello was not part of the ensemble cast when Season 5 began. Like Susan Lewis's second exit, her character's departure was mentioned but not depicted: in the season premiere, "Day for Knight," Carter explains to new medical student Lucy Knight that the locker she is inheriting previously belonged to Anna Del Amico, who is working in a pediatric ER in Philadelphia, where she has family and a boyfriend.
George Clooney left the show in the Season 5 episode "The Storm, Part 2," when his character, Doug Ross, quit before being fired for his involvement in a patient's death. Clooney made a cameo appearance in the Season 6 episode "Such Sweet Sorrow" when his character reunited with Carol Hathaway and appeared in the Season 15 episode "Old Times" where his character was the attending physician caring for a terminal organ donor.
Gloria Reuben departed early in Season 6, in the episode "The Peace of Wild Things," when her character, Jeanie Boulet, decided to become a stay-at-home mom and care for her newly adopted HIV-positive baby. Reuben returned with her child in the Season 14 episode "Status Quo".
Kellie Martin, who played medical student Lucy Knight, left the series midway through Season 6 in the episode "All In The Family," when her character was killed by a patient suffering from undiagnosed schizophrenia; his psychotic break occurred before a backed-up psychiatry department could arrive in the ER for a consult.
Julianna Margulies left the show at the end of Season 6, in the episode "Such Sweet Sorrow," when her character, Carol Hathaway, decided on the spur of the moment to go to Seattle, Washington, and reunite with Doug Ross, her true love and the father of her twin daughters. Margulies returned in the Season 15 episode "Old Times," with her character coordinating transplant efforts from a single organ donor.
Erik Palladino departed early in Season 8, in the episode "Never Say Never," after his character, Dave Malucci, was fired for inappropriate conduct.
Eriq La Salle's character, Peter Benton, departed in the Season 8 episode "I'll Be Home For Christmas." He took a job with a set schedule at another hospital in order to spend more time with his son, Reese, and his girlfriend, former fellow ER doctor Cleo Finch. La Salle returned for two more episodes in Season 8 and then again for two episodes in Season 15, including the series finale.
Michael Michele's character, Cleo Finch, departed in the Season 8 episode "I'll Be Home For Christmas" with her boyfriend, and fellow doctor, Peter Benton, after having previously taken a job at the same hospital. Michele made a cameo appearance in the Season 8 episode "On the Beach" at Mark Greene's funeral.
Anthony Edwards's character, Mark Greene, died of a brain tumor in Season 8's penultimate episode, "On the Beach." Unusually, Anthony Edwards was credited in the following episode "Lockdown." Edwards returned in the Season 15 episode "Heal Thyself" where he appeared in multiple flashback scenes to give insight into the past of Angela Bassett's character.
Paul McCrane's character, Robert Romano, whose arm had been severed just above the elbow by a helicopter's tail rotor in the Season 9 premiere "Chaos Theory," was killed in the Season 10 episode "Freefall." A helicopter that was taking off from the hospital roof was buffeted by strong winds, causing it to crash on the roof and plummet over the side of the building; it fell into a crowded ambulance bay and landed squarely on Romano. McCrane returned in the Season 15 episode "Heal Thyself" in a cameo during flashbacks.
Sharif Atkins left the series in the Season 10 episode "Where There's Smoke," when his character, Michael Gallant, revealed that the Army was sending him to Iraq. Atkins returned for two episodes during Season 11 where he is seen serving duty in Iraq and then for four episodes during Season 12 when he marries Neela Rasgotra and then returns to Iraq where he is killed by an improvised explosive device while serving a second tour.
Alex Kingston's character, Elizabeth Corday, departed early in Season 11 in the episode "Fear" after getting in trouble for performing an illegal organ donation procedure; rather than being summarily fired, County offered her a demotion to a non-tenured position, but she turned it down and opted to return to England instead. In an interview with Britain's Radio Times magazine, Kingston spoke of being written off the show due to her age, a statement that sparked some controversy. She later withdrew that claim. Kingston returned for two episodes in Season 15, including the series finale.
Ming-Na departed midway through Season 11 in the episode "Twas The Night" when her character, Jing-Mei Chen, resigned in order to take care of her ailing father, whom she later euthanized. This was the second time her character left County General: in Season 1, medical student "Deb" Chen appeared in an eight episode story arc which concluded with her leaving medical school after accidentally leaving a guide wire in a patient's chest, deciding she was better suited to research than to applied medicine.
Noah Wyle left in the Season 11 finale, "The Show Must Go On." His character, John Carter, having received tenure at County, decided to reunite with his girlfriend Kem Likasu. Wyle returned for four episodes during Season 12 where he is seen practicing medicine in Darfur and then for five episodes during Season 15 when he needs a kidney transplant.
Laura Innes left midway through Season 13 in the episode "A House Divided," when a reluctant Luka Kovač was forced by budget cuts to fire her character, Kerry Weaver. After bracing for a battle to keep her position, and in spite of the fact that Kovač realized he must find a way to keep her on staff, Weaver ultimately decided to resign from County and accept a job offer from a television station in Miami, Florida. Innes returned for two episodes in Season 15, including the series finale.
Shane West left in the Season 13 finale, "The Honeymoon is Over," after his character, Ray Barnett lost both his legs and returned to Baton Rouge with his mother to recuperate. West returned for three episodes during Season 15 when his character reunited with Neela Rasgotra.
Goran Visnjic, who played the character of Luka Kovač, departed in the season finale of Season 13 when he left for Croatia to care for his ailing father. He returned for seven episodes in Season 14 to wrap up his medical storyline and then made a brief appearance in Season 15's "Book of Abby" where he, Abby, and their son Joe embark on their new life together.
Mekhi Phifer departed in the Season 15 premiere when his character, Gregory Pratt, died in the ER as the result of blast injuries suffered in an ambulance explosion in the Season 14 finale.
Maura Tierney, who played the character of Abby Lockhart, departed early in Season 15 in the episode "Book of Abby" with her TV husband Luka Kovač. Along with their son Joe, they presumably headed to Boston, where Abby had accepted a new job. She attempted to leave the ER quietly, however the rest of the staff made it known how much they would miss her. Nurse Haleh Adams showed Abby a hidden wall with the locker labels of all the past staff members since season one, with the exceptions of Carter and Boulet. Other names on the wall include departed former characters as well as some prominent writers and producers. Abby then left the ER and met Luka and her son Joe outside to embark on their new life together. Tierney returned in the Season 15 episode "Shifting Equilibrium" in a cameo during a phone conversation with Neela Rasgotra.
Supporting cast
Desk clerks and other non-medical hospital staff
| Actor/Actress | Character Name | Character Position | Years of Appearance |
| Julia Dupree | Hospital Chaplain | 2007–2008 | |
| Jerry Markovic | Desk Clerk | 1994–1999; 2002–2006; 2008–2009 | |
| Javier | Desk Clerk | 2007–2008 | |
| Andrew "Andy" | Desk Clerk Temp | 1999–2000 | |
| Kobe "Kubby" Ekabo | Hospital cafeteria worker and wife of Mobalage | 1999 | |
| K.J. Thibeaux | Volunteer | 2005–2006 | |
| Nicole | Runner for Central Supplies and Luka's girlfriend | 2001 | |
| Frank Martin | Desk Clerk | 2000–2009 | |
| Bogdana "Bob" Liwecki | ER Aide/Desk Clerk; Former Vascular Surgeon in Poland | 1994–1995 | |
| Dr Everett Daniels | Hospital Board Member | 2008 | |
| Desk Clerk, also Mark Greene's lover | 1997–1998 | ||
| Mobalage Ekabo | Custodian | 1999 | |
| 2004–2006 | |||
| Miranda "Randi" Fronczak | Desk Clerk | 1995–2003 | |
| Rolando | Desk Clerk | 1995–1996 | |
| E Ray Bozman | Desk Clerk/Trainee Nurse | 1995–1997 | |
| Timmy Rawlins | Desk Clerk | 1994–1995, 2006–2007 | |
| Liza | Surgical Night Clerk | 2005 | |
| Pamela Sinha | Amira | Desk Clerk | 1999–2001, 2003–2005 |
| Diane Leeds | Risk Management Administrator & Doug Ross's girlfriend | 1995 |
Family members and friends
| Actor/Actress | Character Name | Character Position | Years of Appearance |
| Jackie Robbins | Sister to Peter Benton | 1995–2001 | |
| Ruth Greene | Mother of Mark Greene. Died early in Season 6. | 1997–1998 | |
| Al Boulet | Husband of Jeanie Boulet. Contracted HIV from adulterous sex, unwittingly passed it on to Jeanie, died offscreen of AIDS in 2008. | 1995–1997 | |
| Al Boulet | Husband of Jeanie Boulet | 1995 | |
| Roxanne Please | Girlfriend of John Carter. | 1998–1999 | |
| Carla Reece | Girlfriend of Peter Benton. Had mental problems, died in a car accident in 2001. | 1996–2001 | |
| Lin Chen | Mother of Jing-Mei Chen. Died in a car crash in China. | 2003 | |
| Mr. Chen. | Father of Jing-Mei Chen. Euthanized by Chen in 2004. | 2003–2004 | |
| David Greene | Father of Mark Greene. | 1997–2000 | |
| Dave Spencer | Boyfriend of Elizabeth Corday | 2004 | |
| Alex Taggart | Son of Samantha Taggart | 2003–2005 | |
| Elaine Nichols | Carter's cousin's ex-wife | 1999 | |
| Steve Curtis | Ex-husband of Samantha Taggart | 2005–2006 | |
| Henry Lewis | Father of Susan Lewis, proved to be a much better parent than his wife. | 1995–1996; 2004 | |
| Ray Ross. | Father of Doug Ross. | 1996 | |
| Maggie Wyczenski | Mother of Abby Lockhart. Maggie suffers from bipolar disorder, and her uncontrolled mental illness had a negative impact on her ability to parent Abby and her younger brother, Eric, who is also bipolar. | 2000–2006 | |
| Helen Kingsley. | Biological mother of Kerry Weaver. Could not accept Kerry's lesbian orientation. | 2005 | |
| Dr Charles Corday | Father of Elizabeth Corday | 1998, 2001–2002 | |
| Charlie Pratt. | Greg Pratt's long-lost father, who Greg finally told that they would never be father and son. | 2005 | |
| Helen Hathaway | Mother of Carol Hathaway. | 1996–1999 | |
| John "Jack" Carter Jr. | Father of John Carter. Wimpy and not respected by his son or his mom. | 2001–2004 | |
| Roger McGrath | Husband of Carla Reece | 2001 | |
| Mrs. Markovic | Mother of Jerry Markovic | 2006 | |
| Jennifer "Jenn" Greene-Simon. | Mark Greene's wife, then ex-wife. One of the most hated, worst-acted characters in the show's history. | 1994–1996, 1996–1998, 2001–2002 | |
| Steve Curtis | Ex-husband of Samantha Taggart | 2004 | |
| Jaspreet | Cousin of Neela Rasgotra | 2008 | |
| Karen Hines | Doug Ross's girlfriend & his father's boss. Prescription drug addict. | 1996 | |
| Rachel Greene | Daughter of Mark Greene | 2001–2002; 2004; 2009 | |
| Colonel James Gallant | Father of Michael Gallant | 2006 | |
| Courtney Brown | Girlfriend of Kerry Weaver | 2006–2007 | |
| Alex Taggart | Son of Samantha Taggart | 2005–2009 | |
| Mike Gates | Father of Tony Gates. Drunk who once screwed up while a fireman and caused a young trainee's death. | 2007 | |
| Sarah Riley | Adoptive daughter of Tony Gates | 2006–2009 | |
| Ajay Rasgotra | Father of Neela Rasgotra | 2004 | |
| Mrs. Rasgotra | Mother of Neela Rasgotra | 2004 | |
| Lin Chen | Mother of Jing-Mei Chen | 2000 | |
| Sarah Ross | Mother of Doug Ross | 1995–1996 | |
| Mary Taggart | Mother of Samantha Taggart | 2009 | |
| Jacey Barnett | Mother of Ray Barnett | 2007 | |
| Eleanor Carter | Mother of John Carter | 2001 | |
| Jesse Robbins | Nephew of Peter Benton | 2000 | |
| Scott Anspaugh | Son of Donald Anspaugh | 1998 | |
| Makemba "Kem" Likasu-Carter. | Girlfriend and later wife of John Carter. Met John on a medical relief mission in the Congo. Fell in love with him and planned to be with him in Chicago, but their relationship never recovered after their son died in utero. | 2003–2005; 2009 | |
| Craig Simon | 2nd husband of Jennifer "Jenn" Greene-Simon | 1995–1996 | |
| Isabelle Corday | Mother of Elizabeth Corday | 2000–2002 | |
| Linda Farrell | Girlfriend of Doug Ross | 1994–1995 | |
| Cookie Lewis | Mother of Susan Lewis. | 1995 | |
| Niko Kovač | Brother of Luka Kovač | 2007 | |
| Gloria Gallant | Mother of Michael Gallant | 2006 | |
| Mae Benton | Mother of Peter Benton | 1994–1995 | |
| Walter Robbins | Brother-in-law to Peter Benton | 1994–1996 | |
| Chase Carter. | Cousin of John Carter. | 1997–1998, 2001 | |
| Eric Wyczenski | Brother of Abby Lockhart | 2002–2003 | |
| Gracie | Grandmother of Samantha Taggart | 2007 | |
| Millicent "Gamma" Carter | Grandmother of John Carter | 1997–2003 | |
| Leon Pratt | Brother of Greg Pratt | 2002–2003 | |
| Richard Lockhart | Ex-husband of Abby Lockhart | 2000–2003 | |
| Florina Lopez | Mother-in-law of Kerry Weaver | 2004 | |
| Barbara Knight | Mother of Lucy Knight | 2000 | |
| Eddie Wyczenski | Father of Abby Lockhart | 2006–2007 | |
| Reese Benton | Son of Peter Benton | 1999–2001; 2009 | |
| Chloe Lewis | Sister of Susan Lewis | 1994–1996; 2002 | |
| Roger McGrath | Husband of Carla Reece | 1998–2001 | |
| Kelly Taggart | Sister of Samantha Taggart | 2009 | |
| Rachel Greene | Daughter of Mark Greene | 1994–2000 | |
| Actress uncredited | Victoria Dubenko | Sister of Lucien Dubenko | 2006 |
Fire fighters, paramedics, police officers, and social workers
| Actor/Actress | Character Name | Character Position | Years of Appearance |
| Wendall Meade | Social Worker | 2004–2005 | |
| Officer Hollis | Police Officer | 2006–2009 | |
| Christine Harms | Paramedic | 1999—2009 | |
| Reilly Brown | EMT | 1996 | |
| Silva | Paramedic | 2000–2001 | |
| Reidy | Paramedic | 2006–2008 | |
| Anders | Paramedic | 2004, 2009 | |
| Greg Powell | Paramedic | 1997–1998 | |
| Ray "Shep" Shepard | Paramedic and Carol's boyfriend in Season 2. | 1995–1996 | |
| Nikki | Paramedic | 2001–2003 | |
| Al Grabarsky | Police Officer | 1995–1996, 1998–2000 | |
| Adele Newman | Social Services Liaison | 1997–2003 | |
| Raul Melendez | Paramedic | 1995–1996 | |
| Pamela Olbes | Paramedic | 1995–2009 | |
| Liz Dade | Social Worker | 2005–2006, 2007, 2008–2009 | |
| Ken Sung | Social Worker | 2003–2004 | |
| Dannaker | Fire Captain | 1998–2002 | |
| Brian Dumar | Paramedic | 1996—2009 | |
| Tony Bardelli | Paramedic | 2003—2009 | |
| Officer Litchman | Police Officer | 2007 | |
| Officer Wilson | Police Officer | 1995, 1996, 1999–2000, 2001–2004, 2006 | |
| Allison Beaumont | Paramedic and Dr. Corday's patient | 1997—1998 | |
| Morales | Paramedic | 1998—2009 | |
| Danny Yau | Police officer | 2005–2006 | |
| Wright | Paramedic | 2006—2007 | |
| Dwight Zadro | Paramedic | 1995—2009 | |
| CFD Lt. Sandy Lopez | Firefighter, later married Kerry Weaver and had their child through AI. Died in an on duty accident | 2001–2004 | |
| Doris Pickman | Paramedic | 1994—2009 | |
| Reggie Moore | Police officer and boyfriend/husband of Jeanie Boulet | 1998–2000; 2008 | |
| Chris Lowe | Paramedic | 1999? |
Notable patients
| Actor/Actress | Character Name | Character Position | Years of Appearance |
| Al Irving | Junk Dealer, Greene's patient | 1994, 2002 | |
| Jules 'Ruby' Rubadoux. | Carter's patient. | 1995, 2005 | |
| Mary Cavanaugh a.k.a. "Madam X" | Alzheimer's disease patient | 1994 | |
| Iris | Allergy patient, Infomercial Director, and briefly Mark Greene's romance interest | 1996 | |
| Herb Spivak. | Lawyer and patient. Helped Mark fend off a civil lawsuit, later returned having lost all his money in a dot-com bust. | 1997, 2005 | |
| Paul Sobricki | Schizophrenic patient who in a psychotic break stabbed both John Carter and Lucy Knight, the wounds leaving Carter injured and with life-long kidney problems and eventually resulted in Lucy's death. | 2000, 2002 | |
| Loretta Sweet | Originally a prostitute; later Secretary/Cancer patient | 1995–1996 | |
| Pablo | Homeless man and frequent patient in ER | 1997–1998; 2000–2003 | |
| Dr. Nate Lennox | ALS patient, Abby Lockheart's teacher in medical school | 2006 | |
| Keith. | Alderman Bright's lover who contracted Syphilis and was treated under the table by Kerry Weaver. | 2003 | |
| Patrick | 1994 | ||
| Alderman John Bright | Alderman for City of Chicago and patient of Kerry Weaver for Syphilis | 2003 |
Others
| Actor/Actress | Character Name | Character Position | Years of Appearance |
| Jimmy Sweet | Son of the patient Loretta Sweet | 1996 | |
| Chris Law | Sues Mark Greene after his brother dies; a suspect in Greene's beating but is not responsible. He and Mark have a heated conversation in which both men admit they're not the reason for the other's misery. | 1997 | |
| Sean O'Brien | Husband of a pregnant patient in Mark Greene's care | 1995 | |
| Dan Harris | Father who was brought in after a car accident with his son | 2001 | |
| Paul Harris | Son who was brought in after a car accident with his father | 2001 | |
| Ms. Murphy | Teen with ectopic pregnancy | 1994 |
Secondary doctors and medical students
| Actor/Actress | Character Name | Character Position | Years of Appearance |
| Dr. Gabriel Lawrence | ER Attending Physician | 1999 | |
| Dr. Jack Kayson | Chief of Cardiology and member of the board. | 1994–1999, 2001–2005, 2007 | |
| Perry | Anesthesiologist | 1994–2004, 2006, 2008 | |
| Dr. Daria Wade | Intern | 2008–2009 | |
| Dr. Janet Coburn | Chief of Obstetrics & Gynecology. | 1994–2009 | |
| Dr. Donald Anspaugh | Chief of Staff, General surgeon and member of the board, Chief of Staff | 1996–2008 | |
| Penny Nicholson | Medical Student | 2004–2006 | |
| Jake Scanlon | Medical Student | 2004–2005 | |
| Rena Trujillo | Pediatrics Intern. Briefly dated Carter in Season 7. | 2001 | |
| Erin Harkins | Medical Student. | 2002–2003 | |
| Dr. Jeremy Lawson | Invasive Radiologist, had a fling with Dr. Corday. | 2004 | |
| Dr. Julia Wise | Intern who was a key figure in the series finale. | 2009 | |
| Dr. David Kotlowitz | Surgeon | 1999 | |
| Boo Bradley | Special Education Student | 2001 | |
| Dr. Alexander Babcock | Anesthesiologist who hated Dr. Corday and vice versa. | 1998–2002 | |
| Dr. Ellis West | SPG Doctor and Kerry Weaver's boyfriend | 1997–1998 | |
| Dr. Megan Rabb | Director of Neo-Natology | 2004, 2006 | |
| Paul Nathan | Medical Student. Turned from a successful business path after being diagnosed with Parkinson's. | 2002 | |
| Dr. Alice Upton | Pathologist | 1996, 1998, 2000–2001, 2003 | |
| Dr. Eddie Dorset | Vascular Surgeon | 2003 | |
| Ivan Fu | Medical student | 1997 | |
| Dr. Carl DeRaad | Chief of Psychiatry | 1999–2001, 2003 | |
| Katy Alvaro | Medical Student | 2006–2007 | |
| Harper Tracy | Medical Student and love interest of Carter in Season 2. | 1995–1996 | |
| Dr. Dennis Gant | Surgical Intern. | 1996–1997 | |
| Dr. Barry Grossman | Orthopedic Surgeon | 2007–2008 | |
| Dr. Maggie Doyle | ER Intern, later resident | 1996–1999 | |
| Dr. Nina Pomerantz | Psychiatrist | 1997 | |
| Dr. Jane Figler | ER Intern, later resident | 2004—2008 | |
| Dr. Dale Edson | Surgeon. | 1996–1999, 2001–2002 | |
| David | Medical Student | 2004 | |
| Dr. Marty Kline | Orthopeadic Surgeon | 2002–2003, 2006 | |
| Dr. Abby Keaton | Pediatric Surgeon | 1996–1997 | |
| James Sasser | Medical student | 1997 | |
| Dr. Nick 'Coop' Cooper | ER Resident | 2003 | |
| Dr. William 'Wild Willy' Swift | Chief of Surgery and ER Chief | 1995, 1998, 2002 | |
| Dr. Steve Flint | Radiologist | 1994–1996, 1999–2000, 2002 | |
| Dr. Kaya Montoya | Intern | 2008–2009 | |
| Dr. Max Rocher | Pediatrician and ex-boyfriend of Anna Del Amico | 1998 | |
| Dr. Victor Clemente | ER attending physician | 2005–2006 | |
| Dr. Greg Fischer | Infectious disease specialist and briefly boyfriend of Jeanie Boulet | 1997 | |
| Mae Lee Park | Surgical Intern | 2006–2007 | |
| Dr. George Henry | Medical student, assigned to Dr. Carter in Season 4 but had no interest in doing anything ER related with his focus on medical research. | 1997, 2005 | |
| Dr. David Morgenstern | Chief of Surgery and Head of the ER | 1994–1998; 2009 | |
| Dr. Dustin Crenshaw | Junior Surgical Attending, | 2006–2008 | |
| Dr. Skye Wexler | Acting Chief Of Emergency Medicine | 2007–2008 | |
| Debbie | Doctor in Africa | 2003–2006 | |
| Dr. Paul Grady | Intern | 2007–2009 | |
| Dr. Kim Legaspi | Psychiatrist who was in a relationship with Kerry Weaver for a short time before being forced out by Dr. Romano's homophobia. | 2000–2001 | |
| Dr. Andrew Wade | Surgical Intern | 2008–2009 | |
| Dr. Lucien Dubenko | Attending Trauma Surgeon; Chief of Surgery. | 2004–2009 | |
| Dr. Harold Zelinsky | Surgical Intern | 2007—2008 | |
| Hope Bobeck | Medical Student. Devout Christian who inspired Archie Morris in various ways, and dated him for a little while. | 2006–2007 | |
| Ludlow | Medical Student | 2004–2005 | |
| Dr. Angela Hicks | Surgical Attending | 1994–1997 | |
| Dr. Ryan Sanchez | Intern | 2008–2009 | |
| Dr. Bettina DeJesus | Radiologist | 2006–2008 | |
| Dr. Carl Vucelich | Senior Vascular Surgeon. | 1995–1996 | |
| Dr. Tracy Martin | Intern | 2008–2009 | |
| Dr. John "Tag" Taglieri | Orthopedic Surgeon | 1994–1995 | |
| Dr. Jessica Albright | Surgical Chief Resident | 2005–2006 | |
| Stanley Mao | Medical student | 2001 | |
| Dr. Paul Myers | Psychiatrist | 1995, 1997–2000, 2003, 2005, 2008 | |
| Dr. Nelson | Psychiatrist | 2004, 2006 | |
| Ari | Anesthesiologist | 2005–2007 | |
| Lester Kertzenstein | Medical student. | 2003–2004 | |
| Dr. David 'Div' Cvetic | Psychiatrist and boyfriend of Susan Lewis | 1994 | |
| Dr. Kevin Moretti | Chief of Emergency Medicine | 2007–2008 | |
| Bernard Gamely | Medical Student | 1998 | |
| Laverne St. John | Medical Student | 2008–2009 | |
| Dr. Amanda Lee | Chief of Emergency Services | 1998–1999 |
Nurses and other medical staff
| Actor/Actress | Character Name | Character Position | Years of Appearance |
| Conni Oligario | ER Nurse | 1994–2003 | |
| Chuny Marquez | ER Nurse | 1995–2009 | |
| Anna Waldron | Nurse | 2002, 2004, 2005 | |
| Frank 'Rambo' Bacon | ICU nurse & Deb's baby's father | 2000 | |
| Lydia Wright | ER Nurse | 1994–2003, 2009 | |
| Malik McGrath | ER Nurse | 1994–2009 | |
| Haleh Adams | ER Nurse | 1994–2009 | |
| NICU Nurse | 2006 | ||
| Mary | ER Nurse | 2000–2008 | |
| Inez | ER Nurse | 2005–2006 | |
| Lynette Evans | Nurse Practitioner | 1998–1999 | |
| Eve Peyton | Chief ER Nurse | 2005 | |
| Charlie 'Chaz' Pratt, Jr. | Emergency Medical Technician, Brother of Greg Pratt | 2005–2009 | |
| Shirley | Surgical Charge Nurse | 1995–2004, 2006—2009 | |
| Nursing Supervisor | 2005, 2008 | ||
| Kit | ICU, Pediatrics and Surgical Nurse | 1996–2003; 2005; 2008 | |
| Chuck Martin | Flight Nurse and boyfriend/husband/ex-husband of Susan Lewis | 2003–2005 | |
| Lily Jarvik | ER Nurse | 1994–2009 | |
| Wendy Goldman | ER Nurse | 1994–1997 | |
| Mary Cain | County Nursing Director | 1996–1997, 2002 | |
| Dawn Archer | ER Nurse | 2006–2009 | |
| Rhonda Sterling | ER Nurse | 1996 | |
| Ben Parker | ER Nurse | 2006–2007 | |
| Dori | Nurse | 2000—2006 | |
| Bjerke | Nurse | 1996; 2000–2003 | |
| Jacy | Nurse | 2001–2008 | |
| Dee McManus | Flight Nurse | 1996, 1999–2001, 2005, 2008 | |
| Yoshi Takata | ER Nurse | 1997–2003 |
Guest stars
Notable guest stars
- Ed Asner in 2003, as Dr. James McNulty, who runs a street clinic
- Kat Dennings in 2006, as Zoe Butler, a victim of parental battering
- Kirsten Dunst in 1996, as Charlie Chemingo, a child prostitute
- Zac Efron in 2003, as Bobby Neville, a gunshot victim
- Lucy Liu in 1995, as Mei-Sun Leow, the mother of a child dying of AIDS
- Chris Pine in 2003, as Levine, a drunk teen patient
- Charlotte Rae in 2008, as Roxanne Gaines
- Susan Sarandon in 2009, as Nora, a grandmother being asked to consent to the donation of her grandchild's organs
- Eric Stonestreet in 2000, as Willie, a man who tried to make his ears look Vulcan
- Charles Tyner in 1999, as Barry Connelly, whose wife hesitates to sign a DNR
- Wallace Shawn in 2009, as Teddy Lempell, who's love potion may have worked with Jerry
- Judy Greer in 2009, as Tildie Mulligan, who drove her car into the lake because the GPS told her to go straight
- Diego Klattenhoff in 2009, as Jay, the best friend of patient, Mr. Walter's, late son.
- Michael Reilly Burke in 2009, as Dick White, the father that provided vodka at his teenage daughter's slumber party
- Brian Haley in 2009, as Chris Salamunovich, the husband of the woman having twins
- Marilu Henner in 2009, as Linda, the obnoxious mother in law who fought with her son's bride at the wedding
Emmy Award recognized guest stars
- Sally Field in 2001, as Maggie Wyczenski, Abby Lockhart's mother.
- Ray Liotta in 2005, as Charlie Metcalf, a regret-ridden, dying alcoholic.
- Rosemary Clooney in 1995, as "Madame X", an Alzheimer's patient.
- Penny Fuller in 1996, as Mrs. Constantine.
- William H. Macy in 1997, as Dr. David Morgenstern.
- Ewan McGregor in 1997, as Duncan Stewart, a convenience store gunman.
- Veronica Cartwright in 1997, as Norma.
- Swoosie Kurtz in 1998, as Tina-Marie Chambliss.
- Alan Alda in 2000, as Dr. Gabriel Lawrence, an Alzheimer's-stricken doctor and one-time teacher of Dr. Kerry Weaver.
- James Cromwell in 2001, as Bishop Stewart, an ailing Roman Catholic bishop who coaxes a confession from Dr. Luka Kovač, before dying from lupus.
- Mary McDonnell in 2002, as Eleanor Carter, the mother of Dr. John Carter.
- Don Cheadle in 2003, as Paul Nathan, a medical student with Parkinson's disease.
- Bob Newhart in 2004, as Ben Hollander, an architecture model maker losing his sight.
- Red Buttons in 1995, 1996, and 2005, as Mr. Jules 'Ruby' Rubadoux.
- James Woods in 2006, as Dr. Nate Lennox a patient with ALS and former teacher of many of the ER doctors.
- Forest Whitaker in 2007, as Curtis Ames, a patient filing a lawsuit against Dr. Luka Kovač.
- Stanley Tucci in 2008, as Dr. Kevin Moretti.
- Ernest Borgnine in 2009, as Paul Manning