Laconi has a French mother and Italian father. He started racing in 1991 in the French 125cc championship. He won this title in 1992, the French 250cc title a year later, and the European 250cc champion in 1994. For 1995 he went to the 250cc World Championship, but was never a front-runner in his two seasons there.
500cc
was his first season on a 500cc Grand Prix bike, but his World Championship season was marred by injury, missing four rounds after being run over twice in a first-turn incident at the A1 Ring. With Red Bull backing he returned for 1998, riding a Yamaha for three years. He finished 10th, 11th and 12th in the series in this time, but won at Valenciain 1999
For he was a factory ApriliaWSBK rider. He led the first lap of the season, but struggled for much of the season on circuits he did not know. Until the final round at Imola his best result was a 4th, but he benefitted from knowing this circuit. He qualified 2nd, and won the second race, after running strongly in race 1 before being taken out by a fall for champion Troy Bayliss. A move to MotoGP for 2002 was not successful, with a best result of 8th, so for he returned to WSBK for the Caracchi Ducati team, doing enough to earn a factory ride for by taking 5 podium finishes, finishing 4th in a relatively weakened championship. He and team-mate James Toseland were clear favourites for the title, which Toseland took at the final round of the season, in spite of Régis taking 5 poles and 7 wins, and having what is seen as the stronger team of mechanics. His season was interrupted by injury, and for he switched to KawasakiPSG-1 Corse. He finished the season behind his two team-mates in the championship, taking 15th place, with Chris Walker in 9th and Fonsi Nieto in 10th. He remained with the team for and finished 10th overall. He continues with the same team for. At Misano the team ran in a localised San Marino livery, but unfortunately both he and team-mate Makoto Tamada crashed in race 1, forcing Laconi to runrace 2 in the conventional green Kawasaki livery. For 2009 Laconi switched to private Ducatis, riding the sole DFX machine. Results were strong early in the season, however he was seriously injured when he crashed heavily during the opening moments of the first practice of the Kyalami round of the World Superbike Championship. As of 20 May 2009 it was reported that Laconi awakened from his medically induced coma and is reported to have full movement in his arms, hands and legs. Laconi has undergone surgery to clasp his cervical vertebrae back together and it is expected he will remain immobile for some time. Laconi returned for an exploratory test for the DFX Corse Ducati Team at Misano in June 2010 following his horrific crash at Kyalami in 2009. Regis had been training on his bicycle and after more than 70 laps with a best time of 1'37"800, he proved that his talent is still intact. But any thoughts of returning to racing for the moment are premature and totally groundless.The friendship that ties Regis to team manager Daniele Carli enabled the test to take place.
