Primera División de México Clausura 2006
Primera División de México ' Clausura 2006''' is a Mexican football tournament - one of two short tournaments that take up the entire year to determine the champion of Mexican football. It began on Friday, January 20, 2006, and ran until April 30, when the regular season ended. Tecos and San Luis inaugurated the season with a match that resulted in a 2-1 victory for Tecos. On May 21, Pachuca defeated San Luis 1-0 and became champions for the fourth time. Although the team fielded one of two top scorers for this season, Sebastian Abreu, Dorados de Sinaloa was relegated to Primera 'A' in a dramatic last game of regular season against San Luis.
Overview
| Team | City | Stadium | - |
| América | Mexico City | Azteca | - |
| Atlante | Mexico City | Azteca | - |
| Atlas | Guadalajara, Jalisco | Jalisco | - |
| Chiapas | Tuxtla Gutiérrez, Chiapas | Víctor Manuel Reyna | - |
| Cruz Azul | Mexico City | Azul | - |
| Guadalajara | Guadalajara, Jalisco | Jalisco | - |
| Morelia | Morelia, Michoacán | Morelos | - |
| Monterrey | Monterrey, Nuevo León | Tecnológico | - |
| Necaxa | Aguascalientes, Aguascalientes | Victoria | - |
| Pachuca | Pachuca, Hidalgo | Hidalgo | - |
| San Luis | San Luis Potosí, S.L.P. | Alfonso Lastras | - |
| Santos Laguna | Torreón, Coahuila | Corona | - |
| Sinaloa | Culiacán, Sinaloa | Banorte | - |
| Toluca | Toluca, State of Mexico | Nemesio Díez | - |
| UAG | Zapopan, Jalisco | Tres de Marzo | - |
| UANL | San Nicolás de los Garza, Nuevo León | Universitario | - |
| UNAM | Mexico City | Olímpico Universitario | - |
| Veracruz | Veracruz, Veracruz | Luis "Pirata" Fuente |
Final standings (groups)
League table
Top goalscorers
Players sorted first by goals scored, then by last name. Only regular season goals listed.| Rank | Player | Club | Goals |
| 1 |  Sebastián Abreu | Sinaloa | 11 |
| 1 |  Salvador Cabañas | Chiapas | 11 |
| 3 |  Ariel González | San Luis | 10 |
| 3 | Emmanuel Villa | Atlas | 10 |
| 5 | César Delgado | Cruz Azul | 9 |
| 5 |  Patricio Galaz | Atlante | 9 |
| 7 | Gustavo Biscayzacú | Veracruz | 8 |
| 8 |  Kléber Boas | América | 7 |
| 8 | Nelson Cuevas | Pachuca | 7 |
| 8 |  Francisco Fonseca | Cruz Azul | 7 |
| 8 | Luis Ángel Landín | Pachuca | 7 |
| 8 | Daniel Ludueña | UAG | 7 |
| 8 | Carlos Ochoa | Chiapas | 7 |
Source:
Results
Playoffs
Bracket
Quarterfinals
Pachuca won 4–3 on aggregate.----
Guadalajara won 6–5 on aggregate.
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San Luis won 1–0 on aggregate.
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Toluca won 3–2 on aggregate.
Semifinals
4–4 on aggregate. Pachuca advanced for being the higher seeded team.----
San Luis won 4–2 on aggregate.