Substituted piperazine


Substituted piperazines are a class of chemical compounds based on a piperazine core. Some are used as recreational drugs and some are used in scientific research.

List of substituted piperazines

Benzylpiperazines

Befuraline, fipexide, and piberaline produce benzylpiperazine as a metabolite.

Phenylpiperazines

''ortho''-Substituted

Enpiprazole is known to produce oCPP as a metabolite.
Enciprazine was initially anticipated to produce oMeOPP as a metabolite, but this turned out not to be the case.

''meta''-Substituted

Trazodone, nefazodone, mepiprazole, and others produce mCPP as a metabolite.

''para''-Substituted

Many azapirones such as buspirone, gepirone, and tandospirone produce 1-PP as a metabolite.