Tomicki was born in 1464 near Poznań, the son of Mikołaj of Tomice, a Chorąży from Poznań, and Anna of Szamotuły. After his father's death in 1478, he went to the court of his uncle, Andrzej Szamotuły, then governor of Poznań. He studied at the cathedral school in Gniezno, before moving to Leipzig around 1486, and shortly after to the Kraków Academy, where he earned his bachelor's degree in 1490, and his magistrature in philosophy three years later in 1493. That same year he travelled to Bologna to study law, finishing his doctorate in 1500. Immediately after graduation he began working in the Roman Curia, becoming chancellor of Cardinal Fryderyk Jagiellończyk, who gave him a number of ecclesiastical benefices, including the archdeaconry of Kraków, despite Piotr's not being a clergyman. After the death of Cardinal Fryderyk, Piotr went to the court of Jan Lubrański, the bishop of Poznań, where he remained between 1503-1506. Then he went to the office of the crown of King Sigismund I the Old, in whose service as secretary he repeatedly traveled as envoy to Hungary, Wallachia, and Pomerania. In 1511 Piotr was ordained a priest, and in 1514 he was consecrated Bishop of Przemyśl. One year later he became Vice-Chancellor of the Crown, an office which he held until his death. In 1515, together with Chancellor Krzysztof Szydłowiecki, he became the main benefactor of a settlement with the Habsburgs. After the death of Jan Lubrański in 1520, he became bishop in Poznań and renounced the bishopric of Przemyśl. He resided in Wielkopolskafor a while, devoting his time to politics and working for the royal court. In 1525, he became bishop of Kraków, while still bishop of Poznań, as well as Apostolic Nuncio, and collector of papal tributes. In 1526 he abdicated his position as bishop in Poznań. In that same year he conducted an amicable agreement between the king and Albert Hohenzollern. Tomicki served as both Bishop of Kraków and Vice-Chancellor of the Crown from 1525, which was inconsistent with the Polish law of Incompatibilitas. It was one of the main reasons for opposition near Szydłowiec during the Execution movement. Piotr Tomicki died in Kraków on 19 October 1535. He was buried in Wawel Cathedral in a chapel, which he himself founded. He is one of the characters on the famous painting by Jan Matejko, Prussian Homage.