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Phenprocoumon
Phenprocoumon
is a long-acting
oral anticoagulant
drug
, a
derivative
of
coumarin
. It is a
vitamin K antagonist
that inhibits
coagulation
by
blocking
synthesis
of
coagulation factors
II
,
VII
,
IX
and X. It is used for the
prophylaxis
and
treatment
of
thromboembolic
disorders
. It is the
standard
coumatin used in
Germany
.
Phenprocoumon is a
4-hydroxycoumarin
and inhibits
vitamin K epoxide reductase
.