In 2003 he founded the Quality and Safety Research Group. He has published over 200 articles and chapters on patient safety and advises the World Health Organization on improving patient safety measurement through WHO's World Alliance for Patient Safety. He started studying hospital-acquired infections in 2001, concluding that a simple 5 item check-list protocol would greatly reduce infections when inserting a central venous catheter; Doctors should:
Wash their hands with soap.
Clean the patient's skin with chlorhexidine antiseptic.
In the Keystone Initiative, a 2003 study by a collection of Michigan hospitals and health organizations, the median rate of infections at a typical ICU dropped from 2.7 per 1,000 patients to zero after three months. The Keystone Initiative published its results in the December, 2006 New EnglandJournal of Medicine. In the first three months of the project, the infection rate in Michigan's ICUs decreased by sixty-six per cent. In the Initiative's first eighteen months, they estimated that 1500 lives and $100 million were saved. These results were sustained for almost four years. Several reasons may explain why a simple checklist protocol is not more widely adapted:
Many physicians do not like being monitored by nurses or otherwise being forced to follow a checklist;
A wish to avoid standardized tasks and bureaucracy; and
A focus by researchers on "more exciting" issues such as disease biology and new treatment therapies.
According to Pronovost,
Recent work
In 2013, Pronovost co-founded Doctella, a startup that provides surgical checklists for patients to improve patient engagement, patient safety, and lead to better health outcomes. Also in 2013, Pronovost advocated for a system of alcohol and drug testing for doctors in a Journal of the American Medical Association article. He has participated in an online course, or MOOC, from Johns Hopkins provided via Coursera. In January 2018, he announced that he would be taking a position at United HealthCare. Shortly after taking the position he was promoted to Chief Medical Officer. Within weeks of taking this position, his departure from the position and the company was confirmed, although no reason was given. In October 2018, he joined University Hospitals as Chief Clinical Transformation Officer.
Honors
In 2008, he was named in Time magazine's 100 most influential people in the world, and was also named a MacArthur Fellow. In 2011, Pronovost was recognized for his outstanding professional achievement and commitment to service with election to membership in the Institute of Medicine, one of the highest honors in the fields of health and medicine. On March 28, 2013, he was named a Gilman Scholar at Johns Hopkins University.
Personal life
Pronovost has two children. His wife, Marlene, is a pediatrician at Johns Hopkins.