The estuarine system covers an area of approximately in total, with an average water depth of about. The Harvey River discharges into the extreme southern end of the elongated Harvey Estuary, which has an area of about. This in turn feeds into the south-western corner of the more northerly Peel Inlet which is roughly circular and occupies an area of about. The Serpentine River and Murray Rivers discharge into the eastern edges of Peel Inlet. A long channel, the Mandurah Estuary which passes through the town of Mandurah, then runs into the ocean. After several decades of severe algal blooms in the estuaries caused by discharge of nutrients from agricultural land and piggeries along the rivers, an artificial channel was constructed and opened in 1994 as the Dawesville Channel. The channel had the effect of allowing saline sea-water to regularly flush the estuary using tidal flows. Whilst the ecology of the estuary has changed markedly due to the flushing process, water quality generally has improved. The catchment area to the east is largely flat coastal plain with about 75% cleared of native vegetation and used for dryland, dairy and beef grazing. Clearing was done in the early days of settlement to allow agricultural expansion. Drainage systems into the three main rivers have been constructed in much of the catchment to remove excess water quickly. Lake Preston, Lake Clifton and the Leschenault Estuary are farther south.
Flora and fauna
The estuary is home to abundant marine wildlife including crustaceans such as the blue swimmer crab and the western king prawn and fish species such as black bream, mulloway, tailor and cobbler. It is occasionally visited by dolphins. The estuary has been identified by BirdLife International as an Important Bird Area because it supports a significant population of fairy terns, is a drought refuge for blue-billed ducks, and sometimes holds over 1% of the world populations of red-necked stints, sharp-tailed sandpipers, banded stilts, red-necked avocets and red-capped plovers.
Recreational use
The estuary is used heavily for recreational boating and fishing with numerous boat ramps and picnic spots along the extensive foreshore with shaded sandy beaches. Houseboats can be hired at Mandurah to explore the estuary and the Murray River. Urban developments along the shores as well as canal developments in Mandurah and at North and South Yunderup pose significant challenges for its successful future management.