Pedunculagin


Pedunculagin is an ellagitannin. It is formed from casuarictin via the loss of a gallate group.

Natural occurrences

Pedunculagin is found in plants in orders in the clade Rosidae. It can be found the pericarp of pomegranates, in the family Lythraceae, in the order Myrtales. It is also found in plants in the order Fagales such as walnuts in the family Juglandaceae, in Alnus sieboldiana and in the Manchurian alder, both species in the family Betulaceae and it is one of the main oak wood ellagitannins along with castalagin, vescalagin, grandinin and roburins A-E. It is also found in the Indian gooseberry, a plant in the family Phyllanthaceae, in the order Malpighiales.
Galloyl pedunculagin can be found in Platycarya strobilacea.

Health effect

It is a highly active carbonic anhydrase inhibitor.

Chemistry

It is an isomer of terflavin B. It can be synthesized.