O'Keefe
O'Keefe is a surname of Irish origin. People with that name include:
- Andrew O'Keefe, Australian TV personality
- Arthur O'Keefe American banker and mayor of New Orleans
- Dan O'Keefe, a former member of the California state Senate
- Daniel O'Keefe, editor and author, original inventor of Festivus
- Daniel J. O'Keefe, American communication and argumentation theory scholar
- Danny O'Keefe,, American singer-songwriter based in Seattle, Washington
- David Dean O'Keefe, Irishman who created stone money and became the virtual king of the island of Yap
- Dennis O'Keefe, American film actor
- Dennis O'Keefe, the mayor of St. Johns, Newfoundland, Canada
- Derrick O'Keefe, Canadian progressive writer, political activist and blogger
- Eamon O'Keefe, English-born Irish former professional footballer
- Eric O'Keefe, American author, editor, and journalist
- Eugene O'Keefe founder of the O'Keefe Brewery in Toronto
- Frank O'Keefe, Australian politician
- Gerald Francis O'Keefe, Catholic bishop of Davenport, Iowa, USA
- James O'Keefe, American conservative videographer
- James O'Keefe , Dr. James O'Keefe, MD: American author and preventive cardiologist
- Jodi Lyn O'Keefe, American actress and model
- John O'Keefe
- Jeremiah Joseph O'Keefe, American politician
- Jeremiah Joseph O'Keefe IV, American politician
- Joseph "Specs" O'Keefe, one of the participants in the Great Brinks Robbery
- Ken O'Keefe, American college football coach
- Kerin O'Keefe American wine critic and author
- Laurence O'Keefe
- Mark O'Keefe , American politician
- Michael A. O'Keefe, Australian-American physicist
- Michael O'Keefe,, American film and television actor
- Michael H. O'Keefe, American politician; convicted felon
- Molly O'Keefe, American author.
- Neil O'Keefe, retired Australian politician and lobbyist
- Ryan O'Keefe, Australian Football League player
- Sean O'Keefe, Chancellor of Louisiana State University, former NASA administrator and aerospace industry executive
- Stephen O'Keefe, Australian cricketer and current New South Wales player
- Richard O'Keefe, computer scientist
- Thomas O'Keefe, American musician known for his work in the group Antiseen
- Walter O'Keefe, American songwriter, actor and syndicated columnist
