Nucleus reuniens
The nucleus reuniens is a component of the thalamic midline nuclear group. In the human brain, it is located in the interthalamic adhesion.
The nucleus reuniens receives afferent input from a large number of structures, mainly from limbic and limbic-associated structures. It sends projections to the medial prefrontal cortex, the hippocampus, and the entorhinal cortex, although there exist sparse connections to many of the afferent structures as well.
The prefrontal cortical-hippocampal connection allows it to regulate neural traffic between them with changes in attentiveness, as well as contribute to associative learning, spatial route planning, resilience to stress and memory generalization.
